Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 15/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 15/20 | 0.44 |
| ▸ | RAB9A | P51151 | 9/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.44 |
| ▸ | RELA | Q04206 | 6/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4820546 | 0.85 | HSD17B10 (0.54) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29057737 | 0.77 | KMT2A (0.54) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1222694 | 0.77 | ALOX15 (0.61) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL1221861 | 0.75 | ALOX15 (0.49) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL9911604 | 0.75 | MEN1 (0.57) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL15503777 | 0.73 | KMT2A (0.67) | ALOX15MEN1KMT2ALMNAMAPT | |
| SCHEMBL18499238 | 0.72 | MEN1 (0.54) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4390142 | 0.70 | HPGD (0.71) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13779277 | 0.70 | HSD17B10 (0.58) | ALOX15MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL13954267 | 0.70 | HPGD (0.50) | MEN1KMT2ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010075356-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-01 | — | — | WO | disclosed |