Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 10/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13779277 | 0.86 | HSD17B10 (0.58) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL3477614 | 0.85 | ALOX15 (0.45) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL29930704 | 0.82 | HSD17B10 (0.62) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL23611759 | 0.82 | HSD17B10 (0.62) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL1528145 | 0.81 | KMT2A (0.55) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL71938 | 0.80 | HSD17B10 (0.60) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL29930951 | 0.80 | HSD17B10 (0.60) | HSD17B10ALDH1A1KDM4EALOX15HPGD | |
| SCHEMBL70294 | 0.80 | HPGD (0.56) | HSD17B10ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL1528729 | 0.78 | GRM4 (0.58) | HSD17B10ALDH1A1KDM4EHPGDRAB9A | |
| SCHEMBL1528353 | 0.75 | KMT2A (0.57) | HSD17B10ALDH1A1KDM4EALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008157844-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-12-24 | — | — | WO | disclosed |