Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467304 | 0.86 | KMT2A (0.53) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3467575 | 0.81 | MEN1 (0.58) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3468120 | 0.80 | L3MBTL1 (0.43) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3476363 | 0.79 | KMT2A (0.46) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3477650 | 0.78 | POLB (0.42) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3467128 | 0.77 | KMT2A (0.44) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3468757 | 0.75 | ALDH1A1 (0.58) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3476631 | 0.74 | KMT2A (0.45) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL3468829 | 0.73 | L3MBTL1 (0.44) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL5439890 | 0.73 | KMT2A (0.80) | KMT2AMEN1POLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |