SCHEMBL3477693

SCHEMBL3477693

C=C[Si](C)(C)O[Si](C)(O[Si](C)(C)C=C)C(C)C=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 1/20 0.35
HTR2A P28223 3/20 0.33
CYP3A4 P08684 2/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
CYP1A2 P05177 1/20 0.33
TRPA1 O75762 1/20 0.33
CYP2C19 P33261 2/20 0.32
NPC1 O15118 1/20 0.32
MTOR P42345 1/20 0.32
TP53 P04637 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
AHR P35869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478041 0.88 MEN1 (0.43) MEN1KMT2ATDP1HTR2ACYP3A4
SCHEMBL3478044 0.88 MEN1 (0.43) MEN1KMT2ATDP1HTR2ACYP3A4
SCHEMBL3478255 0.88 MEN1 (0.43) MEN1KMT2ATDP1HTR2ACYP3A4
SCHEMBL3478256 0.88 MEN1 (0.43) MEN1KMT2ATDP1HTR2ACYP3A4
SCHEMBL3472250 0.78 MEN1 (0.42) MEN1KMT2ATDP1HTR2ACYP3A4
SCHEMBL9615879 0.75 MEN1 (0.39) MEN1KMT2ACYP3A4MMP1MMP9
SCHEMBL9615878 0.75 MEN1 (0.39) MEN1KMT2ACYP3A4MMP1MMP9
SCHEMBL16912868 0.74 MEN1 (0.42) MEN1KMT2ATDP1HTR2ACYP3A4
SCHEMBL3734441 0.73 MEN1 (0.41) MEN1KMT2ATDP1HTR2ACYP3A4
SCHEMBL3734443 0.73 MEN1 (0.41) MEN1KMT2ATDP1HTR2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4135623-B1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT INC (US) 2026-04-08 EP disclosed
US-20260069403-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RXSIGHT, INC. (US) 2026-03-12 US disclosed
US-20240252311-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT, INC. 2024-08-01 US disclosed
EP-4294325-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RxSight, Inc. (US) 2023-12-27 EP disclosed
EP-4135623-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RxSight, Inc. (US) 2023-02-22 EP disclosed
WO-2022177821-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RXSIGHT, INC. (US) 2022-08-25 WO disclosed
US-20210322152-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT, INC. (US) 2021-10-21 US disclosed
WO-2021211888-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH ADHESION PROMOTER RXSIGHT, INC. (US) 2021-10-21 WO disclosed
US-20210251744-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE RXSIGHT, INC. (US) 2021-08-19 US disclosed
EP-2396355-B1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN INC (US) 2018-05-23 EP disclosed
US-8680172-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2014-03-25 US disclosed
US-20130245756-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS LILLY MING INTERNATIONAL, INC. 2013-09-19 US disclosed
US-8430928-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2013-04-30 US disclosed
US-20120245684-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2012-09-27 US disclosed
US-8222360-B2 Copolymers for intraocular lens systems VISIOGEN, INC. (US) 2012-07-17 US disclosed
US-20100211170-A1 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 US disclosed
WO-2010093823-A2 COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS VISIOGEN, INC. (US) 2010-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260069403-A1 COMPOSITE LIGHT ADJUSTABLE INTRAOCULAR LENS WITH DIFFRACTIVE STRUCTURE IGLV6-57, SMCHD1, UACA MEN1 709/4885KMT2A 989/4885TDP1 3723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.