SCHEMBL3472250

SCHEMBL3472250

CO[Si](C)(OC)C(C)C=Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TRPA1 O75762 2/20 0.41
CYP1A2 P05177 3/20 0.39
CYP2C19 P33261 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
HTR2A P28223 3/20 0.38
NFE2L2 Q16236 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3472344 0.85 MEN1 (0.42) MEN1KMT2ATRPA1CYP1A2TDP1
SCHEMBL80330 0.83 TRPA1 (0.42) MEN1KMT2ATRPA1CYP1A2TDP1
SCHEMBL80331 0.83 TRPA1 (0.42) MEN1KMT2ATRPA1CYP1A2TDP1
SCHEMBL16912868 0.81 MEN1 (0.42) MEN1KMT2ATRPA1CYP1A2CYP2C19
SCHEMBL3477693 0.78 MEN1 (0.43) MEN1KMT2ATRPA1CYP1A2CYP2C19
SCHEMBL8600084 0.77 MEN1 (0.41) MEN1KMT2ACYP1A2HTR2AALDH1A1
SCHEMBL2144291 0.77 MEN1 (0.41) MEN1KMT2ACYP1A2HTR2AALDH1A1
SCHEMBL16912872 0.77 MEN1 (0.41) MEN1KMT2ACYP1A2HTR2AALDH1A1
SCHEMBL3734443 0.76 MEN1 (0.41) MEN1KMT2ATRPA1CYP1A2CYP2C19
SCHEMBL3734441 0.76 MEN1 (0.41) MEN1KMT2ATRPA1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11597789-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2023-03-07 US claimed
US-11092574-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2021-08-17 US claimed
US-20190056360-A1 MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES WATERS TECHNOLOGIES CORPORATION 2019-02-21 US claimed
US-10119944-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2018-11-06 US claimed
US-20150204824-A1 MATERIALS FOR HYDROPHILIC INTERACTION CHROMATOGRAPHY AND PROCESSES FOR PREPARATION AND USE THEREOF FOR ANALYSIS OF GLYCOPROTEINS AND GLYCOPEPTIDES WATERS TECHNOLOGIES CORPORATION 2015-07-23 US claimed
US-7842498-B2 Hydrophobic surface chip BIO-RAD LABORATORIES, INC. (US) 2010-11-30 US claimed
US-7517496-B2 Latex based adsorbent chip BIO-RAD LABORATORIES, INC. (US) 2009-04-14 US claimed
JP-4150673-B2 2008-09-17 JP claimed
EP-1483794-A4 LATEX BASED ADSORBENT CHIP CIPHERGEN BIOSYSTEMS INC (US) 2006-05-03 EP claimed
JP-2005509155-A 2005-04-07 JP claimed
EP-1451554-A4 HYDROPHOBIC SURFACE CHIP CIPHERGEN BIOSYSTEMS INC (US) 2004-12-15 EP claimed
EP-1483794-A2 LATEX BASED ADSORBENT CHIP Ciphergen Biosystems, Inc. (US) 2004-12-08 EP claimed
EP-1451554-A1 HYDROPHOBIC SURFACE CHIP Ciphergen Biosystems, Inc. (US) 2004-09-01 EP claimed
WO-2003079402-A2 LATEX BASED ADSORBENT CHIP CIPHERGEN BIOSYSTEMS, INC. (US) 2003-09-25 WO claimed
US-20030124371-A1 Hydrophobic surface chip CIPHERGEN BIOSYSTEMS, INC. 2003-07-03 US claimed
WO-2003040700-A1 HYDROPHOBIC SURFACE CHIP CIPHERGEN BIOSYSTEMS, INC. (US) 2003-05-15 WO claimed
US-20030032043-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-02-13 US claimed
US-20030017464-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-01-23 US claimed
US-12365751-B2 Materials for hydrophilic interaction chromatography and processes for preparation and use thereof for analysis of glycoproteins and glycopeptides WATERS TECHNOLOGIES CORPORATION (US) 2025-07-22 US disclosed
US-20030017464-A1 Latex based adsorbent chip CIPHERGEN BIOSYSTEMS, INC. 2003-01-23 US disclosed