Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162237 | 0.82 | L3MBTL1 (0.41) | KMT2AL3MBTL1 | |
| SCHEMBL2968353 | 0.82 | L3MBTL1 (0.41) | KMT2AL3MBTL1 | |
| SCHEMBL997079 | 0.82 | L3MBTL1 (0.41) | KMT2AL3MBTL1 | |
| SCHEMBL1009027 | 0.77 | PDK2 (0.58) | KDM4EPOLBF2PDK2RAB9A | |
| SCHEMBL2657776 | 0.75 | KDM4E (0.41) | KDM4EMEN1KMT2APPARAFDPS | |
| SCHEMBL28638507 | 0.73 | KDM1A (0.47) | KDM4EPOLBMEN1KMT2A | |
| SCHEMBL16491284 | 0.72 | LSS (0.50) | KDM4EPOLBPDK2RAB9AMEN1 | |
| SCHEMBL4512069 | 0.71 | TSHR (0.41) | KDM4EF2PDK2ALDH1A1 | |
| SCHEMBL19609158 | 0.71 | MAPT (0.49) | KDM4ERAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8771876 | 0.70 | KDM4E (0.41) | KDM4EPOLBF2PDK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |