Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 2/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | AKT1 | P31749 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997079 | 1.00 | L3MBTL1 (0.41) | L3MBTL1HSD11B1OPRM1PKMCTSS | |
| SCHEMBL2968353 | 1.00 | L3MBTL1 (0.41) | L3MBTL1HSD11B1OPRM1PKMCTSS | |
| SCHEMBL6565280 | 0.82 | HSD11B1 (0.38) | L3MBTL1HSD11B1OPRM1PKMNPSR1 | |
| SCHEMBL6565283 | 0.82 | HSD11B1 (0.38) | L3MBTL1HSD11B1OPRM1PKMNPSR1 | |
| SCHEMBL3477709 | 0.82 | KDM4E (0.41) | L3MBTL1KMT2A | |
| SCHEMBL4550640 | 0.81 | ALDH1A1 (0.41) | L3MBTL1KMT2ANPSR1 | |
| SCHEMBL495877 | 0.80 | MEN1 (0.44) | L3MBTL1OPRM1PKMKMT2A | |
| SCHEMBL3459106 | 0.80 | MEN1 (0.44) | L3MBTL1OPRM1PKMKMT2A | |
| SCHEMBL5142449 | 0.80 | MEN1 (0.44) | L3MBTL1OPRM1PKMKMT2A | |
| SCHEMBL19260910 | 0.79 | OPRM1 (0.45) | L3MBTL1HSD11B1OPRM1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358198-A1 | HYDROXYETHYLAMINO SULFONAMIDE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2011-08-24 | — | — | EP | disclosed |
| WO-2011061590-A1 | NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2011-05-26 | — | — | WO | disclosed |
| EP-1599574-A4 | BIOTRANSFORMATION OF COMPOUNDS USING NON-PROKARYOTIC MICROALGAE | TETHYS RES LLC (US) | 2007-09-12 | — | — | EP | disclosed |
| EP-1599574-A2 | BIOTRANSFORMATION OF COMPOUNDS USING NON-PROKARYOTIC MICROALGAE | Tethys Research LLC (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004081176-A2 | BIOTRANSFORMATION OF COMPOUNDS USING NON-PROKARYOTIC MICROALGAE | TETHYS RESEARCH LLC (US) | 2004-09-23 | — | — | WO | disclosed |