Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | TACR2 | P21452 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11907411 | 0.91 | PTGS1 (0.48) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL17372500 | 0.84 | ALOX5 (0.32) | PTGS2PTGS1ALOX5ALDH1A1 | |
| SCHEMBL8921829 | 0.83 | EPHX2 (0.57) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL16753020 | 0.83 | EPHX2 (0.57) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL30889345 | 0.83 | EPHX2 (0.57) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL3924849 | 0.83 | EPHX2 (0.57) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL10878735 | 0.83 | EPHX2 (0.57) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL3394938 | 0.81 | EPHX2 (0.54) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL20860694 | 0.79 | EPHX2 (0.54) | EPHX2PTGS2PTGS1ALOX5MAPT | |
| SCHEMBL12194495 | 0.79 | EPHX2 (0.54) | EPHX2PTGS2PTGS1ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257601-B1 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | ECOLE POLYTECHNIQUE FED LAUSANNE EPFL (CH) | 2019-04-10 | — | — | EP | disclosed |
| US-9716240-B2 | High molecular extinction coefficient metal dyes | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2017-07-25 | — | — | US | disclosed |
| US-20110062541-A1 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | Changchun Applied Chemistry Institute of Chinese Academy of Sciences (CN) | 2011-03-17 | — | — | US | disclosed |
| EP-2257601-A2 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | Ecole Polytechnique Fédérale de Lausanne (EPFL) (CH) | 2010-12-08 | — | — | EP | disclosed |
| WO-2009107100-A2 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2009-09-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110062541-A1 | HIGH MOLECULAR EXTINCTION COEFFICIENT METAL DYES | ANXA5, TRPM5, EPCAM | EPHX2 4336/4885PTGS2 3111/4885PTGS1 3723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.