SCHEMBL3477831

SCHEMBL3477831

Nc1cc(CCO)c(N)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 6/20 0.55
▸ KMT2A Q03164 6/20 0.55
▸ MAPT P10636 5/20 0.55
▸ THRB P10828 4/20 0.55
▸ MAPK1 P28482 4/20 0.55
▸ MCL1 Q07820 3/20 0.55
▸ NPSR1 Q6W5P4 3/20 0.55
▸ PKM P14618 2/20 0.55
▸ GRK6 P43250 1/20 0.55
▸ KDM4E B2RXH2 1/20 0.55
▸ USP2 O75604 1/20 0.55
▸ ADORA2A P29274 5/20 0.50
▸ CSNK1A1 P48729 2/20 0.50
▸ CSNK1D P48730 2/20 0.50
▸ CSNK1G1 Q9HCP0 2/20 0.50
▸ MAOA P21397 2/20 0.50
▸ FGR P09769 1/20 0.50
▸ PIM1 P11309 1/20 0.50
▸ DYRK1A Q13627 1/20 0.50
▸ HIPK2 Q9H2X6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30118083 1.00 MEN1 (0.55) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL11591306 0.86 AURKA (0.54) MEN1KMT2AMAPTTHRBMAPK1
Methylamine SCHEMBL27662124 0.83 MEN1 (0.50) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL10396192 0.82 MEN1 (0.49) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL10865318 0.80 MEN1 (0.47) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL16145028 0.79 ALDH1A1 (0.58) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL10871129 0.77 MEN1 (0.50) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL2313177 0.76 MEN1 (0.48) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL8801925 0.76 MAPT (0.44) MEN1KMT2AMAPTTHRBMAPK1
SCHEMBL8719818 0.76 GNG2 (0.47) MEN1KMT2AMAPTTHRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115485240-A Self-tanning compositions containing alkyl sulfonates and methods thereof 花王株式会社 2022-12-16 — — CN disclosed
CN-115461331-A Self-tanning composition containing aromatic sulfonate and method thereof 花王株式会社 2022-12-09 — — CN disclosed
EP-3993761-A1 COMPOSITION COMPRISING A NATURAL DYE, A HYDRAZONO AND/OR AZO CATIONIC SYNTHETIC DIRECT DYE AND AN AROMATIC COMPOUND L'OREAL (FR) 2022-05-11 — — EP disclosed
CN-107548301-B Composition containing menthol as soothing agent 西姆莱斯股份公司 2021-05-11 — — CN disclosed
WO-2021004948-A1 COMPOSITION COMPRISING A NATURAL DYE, A HYDRAZONO AND/OR AZO CATIONIC SYNTHETIC DIRECT DYE AND AN AROMATIC COMPOUND L'OREAL (FR) 2021-01-14 — — WO disclosed
WO-2021004950-A1 COMPOSITION COMPRISING A NATURAL DYE, A TRIARYLMETHANE DIRECT DYE AND AN AROMATIC COMPOUND L'OREAL (FR) 2021-01-14 — — WO disclosed
CN-107257797-B Use of azomethines bearing two pyrazolopyridine units for dyeing keratin fibres 欧莱雅 2020-04-17 — — CN disclosed
EP-3474815-A1 PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2019-05-01 — — EP disclosed
EP-3475278-A1 (DIS)SYMMETRIC AZOMETHINE-TYPE DIRECT DYE COMPRISING AT LEAST ONE PYRAZOLOPYRIDINE UNIT, PROCESS FOR DYEING KERATIN FIBERS USING THIS DYE L'OREAL (FR) 2019-05-01 — — EP disclosed
WO-2017220676-A1 PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2017-12-28 — — WO disclosed
EP-2642976-A2 PROCESS FOR STRIPPING KERATIN FIBRES USING A COMPOSITION COMPRISING A SULFINIC ACID DERIVATIVE AND AN ACIDIC AQUEOUS COMPOSITION L'Oréal (FR) 2013-10-02 — — EP disclosed
WO-2013071192-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2013-05-16 — — WO disclosed
WO-2012069599-A2 PROCESS FOR STRIPPING KERATIN FIBRES USING A COMPOSITION COMPRISING A SULFINIC ACID DERIVATIVE AND AN ACIDIC AQUEOUS COMPOSITION L'OREAL (FR) 2012-05-31 — — WO disclosed
WO-2012069639-A2 COMPOSITION FOR TREATING KERATIN FIBRES COMPRISING A CATIONIC SURFACTANT COMPRISING A HYDROXYLATED CHAIN L'OREAL (FR) 2012-05-31 — — WO disclosed
WO-2010142776-A1 N-OXIDIZED AZOMETHINE DIRECT DYES OR REDUCED PRECURSORS OF THESE DYES OBTAINED FROM SECONDARY, N-ALKYLAMINATED PARA-PHENYLENEDIAMINES, METHOD OF HAIR DYEING USING THESE DYES L'OREAL (FR) 2010-12-16 — — WO disclosed
EP-1889605-B1 Tinctorial composition containing a direct dye and an amphoteric polymer comprising units of acrylamide, dialkyldiallylammonium halide and vinyl carboxylic acid OREAL (FR) 2009-12-09 — — EP disclosed
EP-1889605-A1 Tinctorial composition containing a direct dye and an amphoteric polymer comprising units of acrylamide, dialkyldiallylammonium halide and vinyl carboxylic acid L'Oréal (FR) 2008-02-20 — — EP disclosed
EP-1877032-A2 INVERT EMULSION COMPRISING AN AQUEOUS SOLUTION OF HYDROGEN PEROXIDE AND AN INERT PHASE WITH WATER SOLUBILITY OF LESS THAN 1 % L'Oréal (FR) 2008-01-16 — — EP disclosed
WO-2006117469-A2 INVERT EMULSION COMPRISING AN AQUEOUS SOLUTION OF HYDROGEN PEROXIDE AND AN INERT PHASE WITH WATER SOLUBILITY OF LESS THAN 1 % L'ORÉAL (FR) 2006-11-09 — — WO disclosed
CN-1541086-A Dyeing compson. for kerationous fibres comprising particular dicationic diazo dye �ź㴫 2004-10-27 — — CN disclosed
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