Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053560 | 0.84 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL7619717 | 0.74 | ABCB1 (0.31) | ABCB1 | |
| SCHEMBL14959986 | 0.71 | IDE (0.31) | ABCB1 | |
| SCHEMBL14312202 | 0.69 | ABCB1 (0.32) | ABCB1 | |
| SCHEMBL22943329 | 0.68 | OGA (0.42) | LGALS8 | |
| SCHEMBL10306468 | 0.66 | HSP90AA1 (0.39) | LGALS8 | |
| SCHEMBL13620870 | 0.66 | HSP90AA1 (0.39) | LGALS8 | |
| SCHEMBL7885428 | 0.66 | HSP90AA1 (0.39) | LGALS8 | |
| SCHEMBL10259547 | 0.66 | HSP90AA1 (0.39) | LGALS8 | |
| SCHEMBL13609342 | 0.66 | HSP90AA1 (0.39) | LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035857-A1 | ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | MERCK SHARP & DOHME CORP. | 2010-02-11 | — | — | US | disclosed |
| EP-2124549-A1 | ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | Merck & Co., Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008085300-A1 | ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | MERCK & CO., INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| EP-1368363-A2 | SYNTHESIS OF CHLOROPHENOL RED GLUCORONIC ACID | Beckman Coulter, Inc. (US) | 2003-12-10 | — | — | EP | disclosed |
| US-6534637-B2 | Generation of phenolsulphonphthalein glucuronic acid for use as tool in cancer diagnosis | BECKMAN COULTER, INC. | 2003-03-18 | — | — | US | disclosed |
| WO-2002064605-A2 | SYNTHESIS OF CHLOROPHENOL RED GLUCORONIC ACID | BECKMAN COULTER, INC. (US) | 2002-08-22 | — | — | WO | disclosed |
| US-20020115128-A1 | Synthesis of chlorophenol red glucuronic acid | BECKMAN COULTER, INC. | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020115128-A1 | Synthesis of chlorophenol red glucuronic acid | GUSB, UGT1A6, UGT1A7 | LGALS8 1096/4885ABCB1 1467/4885 |
| US-20100035857-A1 | ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS | NPC1L1, HMGCR, PCSK9 | LGALS8 1856/4885ABCB1 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.