SCHEMBL3478

SCHEMBL3478

Cc1cn([C@H]2C[C@H](O)[C@@](F)(C(O)(F)F)O2)c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 7/20 0.49
DHFR P00374 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3092310 0.84 TK1 (0.48) TK1
SCHEMBL11121219 0.81 TK1 (0.46) TK1
SCHEMBL2056793 0.81 TK1 (0.52) TK1
SCHEMBL2056794 0.81 TK1 (0.52) TK1
SCHEMBL21345227 0.80 TK1 (0.54) TK1
SCHEMBL3281 0.80 TK1 (0.50) TK1DHFR
SCHEMBL9416243 0.80 TK1 (0.45) TK1
SCHEMBL9392097 0.80 POLB (0.49) TK1DHFR
SCHEMBL2885 0.79 TK1 (0.50) TK1DHFR
SCHEMBL7543825 0.79 TK1 (0.46) TK1DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4220 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083840-A1 METHODS FOR ABLATING MYELOID DERIVED SUPPRESSOR CELLS USING NEO-201 ANTIBODY PREC BIOLOGICS INC (US) 2026-03-26 US claimed
CN-121570613-A Functionalized nano-particles loaded with antiviral drugs, collagen-based hydrogel eye drops based on in-situ catalytic oxygen production, and preparation method and application thereof 四川大学 2026-02-27 CN claimed
WO-2026043843-A1 TETRAHYDROPYRIMIDINE (THP) IONIZABLE LIPIDS FOR EFFICIENT MRNA DELIVERY THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (US) 2026-02-26 WO claimed
US-20250242040-A1 ALBUMIN CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF Suzhou KangDeRui Pharmaceutical, Ltd. (CN) 2025-07-31 US claimed
CN-119403836-A Methods for eliminating myeloid-derived suppressor cells using NEO-201 antibodies 精密生物制品股份有限公司 2025-02-07 CN claimed
EP-4499710-A1 METHODS FOR ABLATING MYELOID DERIVED SUPPRESSOR CELLS USING NEO-201 ANTIBODY Precision Biologics, Inc. (US) 2025-02-05 EP claimed
WO-2024264038-A2 NEUTRALIZING ANTI-SARS-COV-2 ANTIBODIES THE ROCKEFELLER UNIVERSITY (US) 2024-12-26 WO claimed
WO-2024036313-A9 ANTI-SARS-COV-2 ANTIBODIES AND METHODS OF USE THEREOF THE ROCKEFELLER UNIVERSITY (US) 2024-12-26 WO claimed
US-20240408071-A1 NOVEL COMBINATION OF SEROTONIN RECEPTOR (5-HTR2B) ANTAGONIST AND AN IMMUNOMODULATOR AND CHEMOTHERAPEUTIC DRUGS FOR INHIBITION OF CANCER NATIONAL CENTRE FOR CELL SCIENCE (IN) 2024-12-12 US claimed
US-20240400714-A1 METHODS AND COMPOSITIONS FOR TARGETING TREG CELLS PREC BIOLOGICS INC (US) 2024-12-05 US claimed
EP-0277270-A2 N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-08-10 EP claimed
EP-0262344-A2 N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-04-06 EP claimed
EP-0262343-A2 N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-04-06 EP claimed
EP-0260428-A2 Cationic surfactants and pharmaceutical compositions containing them MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-23 EP claimed
EP-0260429-A2 N-alkylated quaternary nitrogen-containing heterocycles, process for their preparation and their use in pharmaceutical compositions MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-23 EP claimed
EP-0258672-A2 Cationic surfactants and pharmaceutical compositions containing them MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-09 EP claimed
EP-0257400-A2 Pharmaceutical compositions containing cationic surfactants MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) 1988-03-02 EP claimed
EP-0126684-A2 Drug delivery system utilizing thermosetting gels MERCK & CO. INC. (US) 1984-11-28 EP claimed
US-4474751-A SUSTAINED RELEASE USING AN ALKYLENEDIAMINE-MODIFIED ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER MERCK & CO., INC. (US) 1984-10-02 US claimed
US-4302535-A Assay for mutagenesis in heterozygous diploid human lymphoblasts MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1981-11-24 US claimed