SCHEMBL3281

SCHEMBL3281

Cc1cn([C@H]2C[C@H](O)[C@@](Br)(C(O)(Br)Br)O2)c(=O)[nH]c1=O

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 7/20 0.50
DHFR P00374 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3478 0.80 TK1 (0.49) TK1DHFR
SCHEMBL2885 0.80 TK1 (0.50) TK1DHFR
SCHEMBL31653059 0.78 TK1 (0.56) TK1
SCHEMBL4420067 0.78 TK1 (0.56) TK1
SCHEMBL4420063 0.78 TK1 (0.56) TK1
SCHEMBL3437022 0.78 TK1 (0.56) TK1
SCHEMBL3437019 0.78 TK1 (0.56) TK1
SCHEMBL2056793 0.77 TK1 (0.52) TK1
SCHEMBL2056794 0.77 TK1 (0.52) TK1
SCHEMBL26270604 0.77 TK1 (0.52) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100080830-A1 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS PSIVIDA INC. (US) 2010-04-01 US claimed
EP-1239840-B1 ANTIVIRAL MEDICATION ALZA CORP (US) 2005-04-06 EP claimed
US-20040115268-A1 Systemic delivery of antiviral agents CONTROL DELIVERY SYSTEMS, INC. 2004-06-17 US claimed
WO-2004043435-A2 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS CONTROL DELIVERY SYSTEMS, INC. (US) 2004-05-27 WO claimed
US-20020071863-A1 Antiviral medication DONG LIANG C (US) 2002-06-13 US claimed
US-5358721-A Antiviral therapy ALZA CORPORATION (US) 1994-10-25 US claimed
US-20250313905-A1 METHODS AND COMPOSITIONS FOR IMPROVED PSYCHOLOGICAL AND RESILIENCE MEASURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-10-09 US disclosed
US-12364717-B2 Compositions and methods for inhibiting seizures THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-22 US disclosed
US-12292445-B2 Methods of selecting subjects for treatment with metabolomic modulators THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-05-06 US disclosed
EP-4525896-A1 METHODS AND COMPOSITIONS FOR IMPROVED PSYCHOLOGICAL AND RESILIENCE MEASURES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-03-26 EP disclosed
WO-2025038777-A2 PROBIOTICS AND METHODS TO REDUCE APPETITE BLOOM SCIENCE, INC. (US) 2025-02-20 WO disclosed
EP-4509174-A2 COMPOSITIONS AND METHODS FOR PROMOTING SKIN HEALTH The Regents of the University of California (US) 2025-02-19 EP disclosed
US-12195814-B2 Cell-free nucleic acids for the analysis of the human microbiome and components thereof THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2025-01-14 US disclosed
WO-2005051234-A2 INJECTABLE SUSTAINED RELEASE IMPLANT HAVING A BIOERODIBLE MATRIX CORE AND A BIOERODIBLE SKIN CONTROL DELIVERY SYSTEMS, INC. (US) 2005-06-09 WO disclosed
EP-1239840-B1 ANTIVIRAL MEDICATION ALZA CORP (US) 2005-04-06 EP disclosed
US-20040176341-A1 Core surrounded by polymer exterior layers, coatings, or skins which are bioerodable or biodegradable; time-release drug delivery device EYEPOINT PHARMACEUTICALS US, INC. 2004-09-09 US disclosed
US-20040115268-A1 Systemic delivery of antiviral agents CONTROL DELIVERY SYSTEMS, INC. 2004-06-17 US disclosed
WO-2004043435-A2 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS CONTROL DELIVERY SYSTEMS, INC. (US) 2004-05-27 WO disclosed
US-20020071863-A1 Antiviral medication DONG LIANG C (US) 2002-06-13 US disclosed
US-5358721-A Antiviral therapy ALZA CORPORATION (US) 1994-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100080830-A1 SYSTEMIC DELIVERY OF ANTIVIRAL AGENTS HAVCR2, MAVS, PGF TK1 18/4885DHFR 46/4885
US-20040176341-A1 Core surrounded by polymer exterior layers, coatings, or skins which are bioerodable or biodegradable; time-release drug delivery device CUTA, PUF60, PGF TK1 2648/4885DHFR 3720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.