Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 3/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2577575 | 0.88 | ALDH1A1 (0.40) | SCN5ACACNA1CCLCN2HTTPARP1 | |
| SCHEMBL27661779 | 0.84 | CLCN2 (0.63) | SCN5ACLCN2HTTTSHRALOX15 | |
| SCHEMBL22289680 | 0.83 | CACNA1C (0.51) | SCN5ACACNA1CCLCN2HTTPARP1 | |
| SCHEMBL28428886 | 0.81 | KDM4E (0.51) | SCN5ACLCN2HTTTSHRALOX15 | |
| SCHEMBL11741895 | 0.80 | PTGS2 (0.50) | SCN5ACACNA1CCLCN2HTTALOX15 | |
| SCHEMBL28046951 | 0.80 | CLCN2 (0.55) | SCN5ACACNA1CCLCN2HTT | |
| Dimethylamine SCHEMBL27639205 | 0.79 | MAPT (0.47) | CLCN2HTTPARP1TSHRKDM4E | |
| SCHEMBL7196230 | 0.78 | SCN5A (0.57) | SCN5ACACNA1CCLCN2HTTTSHR | |
| SCHEMBL25022848 | 0.78 | ALDH1A1 (0.44) | PARP1TSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6883362 | 0.78 | KDM4E (0.55) | HTTPARP1TSHRHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101432268-B | 4- (2-amino-1-hydroxyethyl) phenol derivatives as beta 2 adrenoreceptor agonists | ALMIRALL LAB | 2011-02-16 | — | — | CN | claimed |
| WO-2010130900-A2 | TRIAMINOPYRIMIDINE DERIVATIVES AS CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2010-11-18 | — | — | WO | claimed |
| CN-101432268-A | 4- (2-amino-1-hydroxyethyl) phenol derivatives as beta 2 adrenoreceptor agonists | ALMIRALL LAB (ES) | 2009-05-13 | — | — | CN | claimed |
| CN-101432268-B | 4- (2-amino-1-hydroxyethyl) phenol derivatives as beta 2 adrenoreceptor agonists | ALMIRALL LAB | 2011-02-16 | — | — | CN | disclosed |
| WO-2010130900-A2 | TRIAMINOPYRIMIDINE DERIVATIVES AS CDC25 PHOSPHATASE INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2010-11-18 | — | — | WO | disclosed |
| CN-101432268-A | 4- (2-amino-1-hydroxyethyl) phenol derivatives as beta 2 adrenoreceptor agonists | ALMIRALL LAB (ES) | 2009-05-13 | — | — | CN | disclosed |