Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | DGKA | P23743 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355681 | 0.86 | NAAA (0.52) | NAAADGKAHTTDNM1ALDH1A1 | |
| SCHEMBL50185 | 0.83 | NAAA (0.81) | NAAADGKAHTTDNM1HTR2C | |
| SCHEMBL2600809 | 0.83 | NAAA (0.73) | NAAADGKAHTTDNM1HTR2C | |
| SCHEMBL11257090 | 0.83 | DGKA (0.61) | NAAADGKADNM1HTR2CALDH1A1 | |
| SCHEMBL14163783 | 0.82 | NAAA (0.59) | NAAADGKAHTTDNM1HTR2C | |
| SCHEMBL15305232 | 0.82 | NAAA (0.59) | NAAADGKAHTTDNM1HTR2C | |
| SCHEMBL727436 | 0.82 | NAAA (0.59) | NAAAHTTALDH1A1 | |
| SCHEMBL28312766 | 0.81 | NAAA (0.64) | NAAADGKAHTTDNM1HTR2C | |
| SCHEMBL3993048 | 0.80 | NAAA (0.86) | NAAADGKAHTTDNM1HTR2C | |
| SCHEMBL12956536 | 0.80 | NAAA (0.86) | NAAADGKAHTTDNM1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015197860-A2 | NOVEL THAPSIGARGIN ANALOGUES AND METHODS OF PREPARING THEM | UNIVERSITY OF COPENHAGEN (DK) | 2015-12-30 | — | — | WO | claimed |
| EP-0296749-A1 | (Substituted aralkyl) heterocyclic compounds | ZENECA LIMITED (GB) | 1988-12-28 | — | — | EP | claimed |
| EP-2396355-B1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN INC (US) | 2018-05-23 | — | — | EP | disclosed |
| US-8680172-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2014-03-25 | — | — | US | disclosed |
| US-20130245756-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | LILLY MING INTERNATIONAL, INC. | 2013-09-19 | — | — | US | disclosed |
| US-8430928-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2013-04-30 | — | — | US | disclosed |
| WO-2013036567-A2 | METHODS, COMPOSITIONS, AND COMPOUNDS FOR THE REDUCTION OF ILLEGAL METHAMPHETAMINE PRODUCTION | JOHNSON BRENT A (US) | 2013-03-14 | — | — | WO | disclosed |
| US-20120245684-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2012-09-27 | — | — | US | disclosed |
| US-8222360-B2 | Copolymers for intraocular lens systems | VISIOGEN, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-20100211170-A1 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010093823-A2 | COPOLYMERS FOR INTRAOCULAR LENS SYSTEMS | VISIOGEN, INC. (US) | 2010-08-19 | — | — | WO | disclosed |
| EP-0650496-B1 | ANTI-INFLAMMATORY COMPOUNDS FOR OPHTHALMIC USE | ALCON LAB INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0768358-A1 | Liquid-crystalline medium | MERCK PATENT GmbH (DE) | 1997-04-16 | — | — | EP | disclosed |
| EP-0596125-A1 | CONDENSED THIOPHENE COMPOUND AND PHARMACEUTICAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4261986-A | ANTIINFLAMMATORY STEROIDS | SYNTEX (U.S.A.) INC. (US) | 1981-04-14 | — | — | US | disclosed |
| EP-0004772-A2 | 4-Halo etianic acids and derivatives thereof, their pharmaceutical use and preparation | SYNTEX (U.S.A.) INC. (US) | 1979-10-17 | — | — | EP | disclosed |
| US-4152149-A | Composite material comprising reinforced aluminum or aluminum-base alloy | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1979-05-01 | — | — | US | disclosed |