SCHEMBL347988

SCHEMBL347988

CCCCCN1CCCCCC1

nearest known ligand 0.95

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.70
GNAI3 P08754 6/20 0.56
GNAO1 P09471 6/20 0.56
GNAI1 P63096 6/20 0.56
LTA4H P09960 1/20 0.48
MAPT P10636 1/20 0.48
HRH1 P35367 1/20 0.47
CYP1A2 P05177 1/20 0.46
MAPK1 P28482 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44723 1.00 HRH3 (0.70) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL6506568 1.00 HRH3 (0.70) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL28208695 1.00 HRH3 (0.70) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL5086108 1.00 HRH3 (0.70) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL6506370 1.00 HRH3 (0.70) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL23682856 0.97 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL11486347 0.97 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
Bromide SCHEMBL10551492 0.97 HRH3 (0.67) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL22151380 0.97 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL27096 0.97 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103073878-B Polyamide composition, and preparation method and application thereof TIANJIN KINGFA NEW MATERIAL CO LTD 2014-12-24 CN claimed
CN-104072981-A Halogen-free flame retardant polyamide material and preparation method thereof Suzhou chuangjia plastic co ltd 2014-10-01 CN claimed
CN-103073878-A Polyamide composition, and preparation method and application thereof TIANJIN JINFA NEW MATERIAL CO LTD 2013-05-01 CN claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US disclosed
US-20230012756-A1 TIME BASED TRIGGERING OF DYNAMIC TEMPLATES KnowBe4, Inc. (US) 2023-01-19 US disclosed
US-20220388980-A1 QUINOLINE INHIBITORS OF RAD52 AND METHODS OF USE UNIV DREXEL (US) 2022-12-08 US disclosed
WO-2021067604-A1 QUINOLINE INHIBITORS OF RAD52 AND METHODS OF USE DREXEL UNIVERSITY (US) 2021-04-08 WO disclosed
US-10758534-B2 Modulators of cystic fibrosis transmembrane conductance regulator VERTEX PHARMACEUTICALS INCORPORATED (US) 2020-09-01 US disclosed
US-20200222406-A1 METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS DALCOR PHARMA UK LTD., STOCKPORT ZUG BRANCH (CH) 2020-07-16 US disclosed
US-20190269683-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2019-09-05 US disclosed
CN-108027353-A SOLID PHASE EXTRACTION, DERIVATIZATION WITH CROWN ETHERS, AND MASS SPECTROMETRY, METHODS, REAGENTS AND KITS 帝肯样品制备股份有限公司 2018-05-11 CN disclosed
US-20060035155-A1 Nonaqueous electrolyte solution for secondary battery and nonaqueous electrolyte secondary battery SANYO ELECTRIC CO., LTD. (JP) 2006-02-16 US disclosed
WO-2005082892-A2 TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2005-09-09 WO disclosed
EP-1535913-A1 NOVEL QUATERNARY AMMONIUM COMPOUNDS Asahi Kasei Pharma Corporation (JP) 2005-06-01 EP disclosed
CN-1171928-C Polyamide resin composition and process for producing the same ������������ʽ���� 2004-10-20 CN disclosed
CN-1275148-A Polyamide resin composition and process for producing the same ASAHI CHEMICAL IND (JP) 2000-11-29 CN disclosed
US-4046909-A Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants MCNEIL LABORATORIES, INCORPORATED (US) 1977-09-06 US disclosed
US-4046909-A Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants MCNEIL LABORATORIES, INCORPORATED (US) 1977-09-06 US disclosed
US-3998958-A Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants MCNEIL LABORATORIES, INCORPORATED (US) 1976-12-21 US disclosed
US-3998958-A Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants MCNEIL LABORATORIES, INCORPORATED (US) 1976-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220388980-A1 QUINOLINE INHIBITORS OF RAD52 AND METHODS OF USE RAD52, RECQL, RAD50 HRH3 2354/4885GNAI3 1409/4885GNAO1 2483/4885
US-20200222406-A1 METHODS FOR TREATING OR PREVENTING CARDIOVASCULAR DISORDERS AND LOWERING RISK OF CARDIOVASCULAR EVENTS HMGCR, PCSK9, FABP3 HRH3 4303/4885GNAI3 1743/4885GNAO1 2521/4885
US-20190269683-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1B, SLC26A4 HRH3 2523/4885GNAI3 222/4885GNAO1 198/4885
US-10758534-B2 Modulators of cystic fibrosis transmembrane conductance regulator CFTR, SCNN1B, SLC26A4 HRH3 2523/4885GNAI3 222/4885GNAO1 198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.