SCHEMBL1260762

SCHEMBL1260762

CCCCCCCCCCN1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 2/20 0.75
▸ GNAI3 P08754 6/20 0.59
▸ GNAO1 P09471 6/20 0.59
▸ GNAI1 P63096 6/20 0.59
▸ LTA4H P09960 1/20 0.52
▸ KDM4E B2RXH2 1/20 0.47
▸ BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL634336 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL1262658 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL11226591 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL1262669 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL11210977 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL9641523 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL23682856 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL1277091 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL22151380 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H
SCHEMBL11224880 1.00 HRH3 (0.75) HRH3GNAI3GNAO1GNAI1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107987104-A Gyphosate herbicice ionic liquid and its preparation and application 浙江省农业科学院 2018-05-04 — — CN claimed
CN-101747259-B Azasugars compounds, synthesis method and applications thereof PEKING UNIVERSITY (CN) 2012-02-15 — — CN claimed
US-20260121095-A1 Advanced Ion Exchange Membranes And Applications Thereof WILLIAMS RICHARD KENT (US) 2026-04-30 — — US disclosed
EP-3527639-B1 A METHOD FOR BONDING A THERMOPLASTIC MATERIAL BY MICROWAVE-IRRADIATION PROIONIC GMBH (AT) 2021-09-08 — — EP disclosed
CN-106029804-B Method for curing adhesives using microwave radiation 普罗奥尼克股份有限公司 2019-09-24 — — CN disclosed
EP-3527639-A1 A METHOD FOR BONDING A THERMOPLASTIC MATERIAL BY MICROWAVE-IRRADIATION proionic GmbH (AT) 2019-08-21 — — EP disclosed
CN-109593089-A The preparation of diaza spiro decane piperidine formyl amine compound and application 西南大学 2019-04-09 — — CN disclosed
US-10201527-B2 Benzimidazole derivatives: preparation and pharmaceutical applications MEI PHARMA, INC. (US) 2019-02-12 — — US disclosed
CN-107987104-A Gyphosate herbicice ionic liquid and its preparation and application 浙江省农业科学院 2018-05-04 — — CN disclosed
US-20170360757-A1 BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS S*BIO PTE LTD. (SG) 2017-12-21 — — US disclosed
US-20170198006-A1 PRMT5 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2017-07-13 — — US disclosed
WO-1999022743-A1 POLY(DIALLYLAMINE)-BASED PHOSPHATE BINDERS GELTEX PHARMACEUTICALS, INC. (US) 1999-05-14 — — WO disclosed
WO-1998029107-A2 POLY(DIALLYLAMINE)-BASED BILE ACID SEQUESTRANTS GELTEX PHARMACEUTICALS, INC. (US) 1998-07-09 — — WO disclosed
EP-0401503-B1 Solid non-hygroscopic trialkylamine oxides ALBEMARLE CORP (US) 1996-01-17 — — EP disclosed
EP-0309844-B1 PROCESS FOR THE PREPARATION OF CHLOROTHIOL FORMIATES BASF Aktiengesellschaft (DE) 1991-12-04 — — EP disclosed
EP-0424965-A1 Amine oxide process ETHYL CORPORATION (US) 1991-05-02 — — EP disclosed
EP-0401503-A2 Solid non-hygroscopic trialkylamine oxides ALBEMARLE CORPORATION (US) 1990-12-12 — — EP disclosed
US-4960934-A Amine oxide process ETHYL CORPORATION (US) 1990-10-02 — — US disclosed
EP-0320694-A2 Amine oxide process ETHYL CORPORATION (US) 1989-06-21 — — EP disclosed
US-4220764-A Preparation of tertiary heterocyclic amines UOP INC. (US) 1980-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10201527-B2 Benzimidazole derivatives: preparation and pharmaceutical applications HDAC5, HDAC1, HDAC8 HRH3 177/4885GNAI3 2163/4885GNAO1 4025/4885
US-20260121095-A1 Advanced Ion Exchange Membranes And Applications Thereof MYOC, MB, MYOF HRH3 2447/4885GNAI3 3402/4885GNAO1 2144/4885
US-20170198006-A1 PRMT5 INHIBITORS AND USES THEREOF PRMT5, PRMT1, PRMT6 HRH3 1607/4885GNAI3 945/4885GNAO1 2511/4885
US-20170360757-A1 BENZIMIDAZOLE DERIVATIVES: PREPARATION AND PHARMACEUTICAL APPLICATIONS HDAC5, HDAC1, HDAC8 HRH3 177/4885GNAI3 2163/4885GNAO1 4025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback