SCHEMBL3480194

SCHEMBL3480194

CC1CCCN2CCN(C)CCCN(CC1)CC2

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.35
LMNA P02545 1/20 0.34
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
PRMT1 Q99873 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4886098 0.87 HTT (0.39) HTTLMNAKDM4ETDP1CARM1
SCHEMBL16356428 0.84 NCF1 (0.37) HTTLMNAKDM4ETDP1CARM1
SCHEMBL10173819 0.82
SCHEMBL12449629 0.82
SCHEMBL12085 0.82
SCHEMBL1116280 0.82 NCF1 (0.36) HTTLMNAKDM4ETDP1CARM1
SCHEMBL19237188 0.79 NCF1 (0.35) HTTLMNAKDM4ETDP1CARM1
SCHEMBL19237191 0.79 NCF1 (0.35) HTTLMNAKDM4ETDP1CARM1
SCHEMBL4311811 0.79 TDP1 (0.38) HTTLMNAKDM4ETDP1PRMT6
SCHEMBL12354598 0.79 TDP1 (0.38) HTTLMNAKDM4ETDP1PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2147042-A1 DENDRITIC MOLECULES The University Of Queensland (AU) 2010-01-27 EP disclosed
WO-2008141357-A1 DENDRITIC MOLECULES THE UNIVERSITY OF QUEENSLAND (AU) 2008-11-27 WO disclosed