SCHEMBL4886098

SCHEMBL4886098

CC1CCCN(C)CCN(C)CCCN(C)CC1

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.39
LMNA P02545 2/20 0.38
KDM4E B2RXH2 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
NCF1 P14598 1/20 0.36
CARM1 Q86X55 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
PRMT1 Q99873 1/20 0.35
PRMT8 Q9NR22 1/20 0.35
ACHE P22303 1/20 0.35
SIGMAR1 Q99720 1/20 0.33
ALDH1A1 P00352 3/20 0.32
PHGDH O43175 1/20 0.32
MGLL Q99685 1/20 0.32
POLB P06746 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16356428 0.97 NCF1 (0.37) HTTLMNAKDM4ETDP1NCF1
SCHEMBL10173819 0.95
SCHEMBL12449629 0.95
SCHEMBL12085 0.95
SCHEMBL1660125 0.90 NCF1 (0.36) HTTLMNATDP1NCF1CARM1
SCHEMBL1116280 0.89 NCF1 (0.36) HTTLMNAKDM4ETDP1NCF1
SCHEMBL10287120 0.87 ACHE (0.41) HTTLMNATDP1NCF1CARM1
SCHEMBL19237188 0.87 NCF1 (0.35) HTTLMNAKDM4ETDP1NCF1
SCHEMBL19237191 0.87 NCF1 (0.35) HTTLMNAKDM4ETDP1NCF1
SCHEMBL3480194 0.87 HTT (0.35) HTTLMNAKDM4ETDP1CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080274074-A1 Method for Controlled Free Radical Polymerization or Copolymerization of Methacrylic and/or Methacrylate Monomers or Exclusively Methacrylic and/or Methacrylate Copolymers ARKEMA FRANCE (FR) 2008-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274074-A1 Method for Controlled Free Radical Polymerization or Copolymerization of Methacrylic and/or Methacrylate Monomers or Exclusively Methacrylic and/or Methacrylate Copolymers PRMT9, MMAB, PRMT8 HTT 3086/4885LMNA 2746/4885KDM4E 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.