SCHEMBL3480359

SCHEMBL3480359

CCc1c(CC)c(Cc2ccc(O)cc2)c(CC)c(CC)c1Cc1ccc(O)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.59
ESR2 Q92731 3/20 0.59
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
MEN1 O00255 1/20 0.48
APAF1 O14727 1/20 0.48
USP2 O75604 1/20 0.48
POLB P06746 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
MAPK1 P28482 1/20 0.48
CASP1 P29466 1/20 0.48
BLM P54132 1/20 0.48
KMT2A Q03164 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TMEM97 Q5BJF2 1/20 0.45
SIGMAR1 Q99720 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1841575 0.80 ESR1 (0.74) ESR1ESR2ALDH1A1HSD17B10MEN1
SCHEMBL1121520 0.78 ESR1 (0.62) ESR1ESR2ALDH1A1L3MBTL1TMEM97
SCHEMBL3480423 0.78 ESR1 (0.62) ESR1ESR2ALDH1A1L3MBTL1TMEM97
SCHEMBL14864969 0.77 ESR1 (0.48) ESR1ESR2ALDH1A1HSD17B10MEN1
SCHEMBL28148524 0.76 ALDH1A1 (0.64) ESR1ESR2ALDH1A1HSD17B10MEN1
SCHEMBL28713 0.76
SCHEMBL36454 0.76 ESR1 (1.00) ESR1ESR2ALDH1A1HSD17B10MEN1
SCHEMBL2969737 0.76 ESR1 (1.00) ESR1ESR2ALDH1A1HSD17B10MEN1
Ammonia Solution, Strong SCHEMBL265238 0.74 ALDH1A1 (0.61) ESR1ESR2ALDH1A1HSD17B10MEN1
Ethane SCHEMBL16114596 0.74 ALDH1A1 (0.61) ESR1ESR2ALDH1A1HSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389630-B2 Curable composition KANEKA CORPORATION (JP) 2013-03-05 US disclosed
EP-1970408-B1 CURABLE COMPOSITION KANEKA CORP (JP) 2011-12-28 EP disclosed
US-20100227949-A1 CURABLE COMPOSITION KANEKA CORPORATION (JP) 2010-09-09 US disclosed
EP-1970408-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2008-09-17 EP disclosed
EP-0758661-B1 Curable epoxy resin compositions ASAHI DENKA KOGYO KK (JP) 2000-03-08 EP disclosed
EP-0610068-B1 Emulsifying epoxy resin composition and curable composition ASAHI DENKA KOGYO KK (JP) 1999-10-27 EP disclosed
EP-0872504-A1 CURABLE EPOXY RESIN COMPOSITION WHICH GIVES FLEXIBLE CURED ARTICLE ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1998-10-21 EP disclosed
EP-0870790-A1 CURABLE EPOXY RESIN COMPOSITION ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1998-10-14 EP disclosed
US-5783644-A CONTAINING MANNICH BASE ASAHI DENKA KOGYO K.K. (JP) 1998-07-21 US disclosed
US-5688876-A REACTION OF PHENOLIC GROUP WITH CARBONYL GROUP AND AMINO COMPOUND FOR MANNICH BASE ASAHI DENKA KOGYO K.K. (JP) 1997-11-18 US disclosed
US-4826895-A Paint composition for under coating NIPPON STEEL CORPORATION (JP) 1989-05-02 US disclosed
US-4736010-A AMINE-CONTAINING AMIDE FORMED FROM CARBOXYL-CONTAINING ACRYLONITRILE-BUTADIENE COPOLYMER, EPOXIDIZED FATTY ESTER AND NITROGEN COMPOUNDS; ADHESION, PEEL-STRENGTH ASAHI DENKA KOGYO K.K. (JP) 1988-04-05 US disclosed
US-4689390-A AMINE-EPOXY ADDUCT REACTED WITH PHENOLIC RESIN, ONE-PACK ASAHI DENKA KOGYO K.K. (JP) 1987-08-25 US disclosed
US-4657947-A COVERING RUSTY METAL SURFACES ASAHI DENKA KOGYO K.K. (JP) 1987-04-14 US disclosed
US-4657953-A CORROSION RESISTANCE ASAHI DENKA KOGYO K.K. (JP) 1987-04-14 US disclosed
EP-0197458-A2 Curable epoxy resin composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1986-10-15 EP disclosed
US-4535103-A POLYEPOXIDES AND EPOXY RESINS CROSSLINKED AND HARDENED WITH PHOSPHOROUS COMPOUNDS, AMINES, AND DIISOCYANATES ASAHI DENKA KOGYO K.K. (JP) 1985-08-13 US disclosed
US-4530947-A A RUSTY METAL-ADHERING CURABLE MIXTURE OF EPOXIDE-POLYHYDROXIDE REACTION PRODUCT, POLYISOCYANATE AND BITUMINOUS MATERIAL ASAHI DENKA KOGYO K.K. (JP) 1985-07-23 US disclosed
US-4340716-A EPOXY RESINS AND HARDENERS ASAHI DENKA KOGYO K.K. (JP) 1982-07-20 US disclosed
US-3950451-A COUPLED PRODUCT OF ALKYLPHENOL AND PHENOL-FORMALDEHYDE-DIAMINE CONDENSATE ASAHI DENKA KOGYO K.K. (JA) 1976-04-13 US disclosed