Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817551 | 0.87 | KMT2A (0.38) | SMN1; SMN2KMT2AHTTMEN1GALR3 | |
| SCHEMBL23636587 | 0.83 | PSEN1 (0.37) | SMN1; SMN2KMT2AHTTMEN1GALR3 | |
| SCHEMBL8397410 | 0.79 | ALDH1A1 (0.43) | SMN1; SMN2KMT2AHTTMEN1GALR3 | |
| SCHEMBL23636597 | 0.75 | PSEN1 (0.39) | SMN1; SMN2KMT2AHTTMEN1GALR3 | |
| SCHEMBL9514033 | 0.74 | CA1 (0.34) | SMN1; SMN2KMT2AHTTMEN1L3MBTL1 | |
| SCHEMBL13021497 | 0.72 | MEN1 (0.42) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL5838052 | 0.71 | CHEK1 (0.50) | SMN1; SMN2KMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL21956083 | 0.70 | MAPT (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL21956082 | 0.70 | MAPT (0.48) | SMN1; SMN2KMT2AMEN1ALDH1A1CA1 | |
| SCHEMBL11876401 | 0.68 | ALDH1A1 (0.41) | SMN1; SMN2KMT2AHTTMEN1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803359-B1 | UV-absorbers for ophthalmic lens materials | ALCON, INC. (CH) | 2010-09-28 | — | — | US | disclosed |