Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23636587 | 0.88 | PSEN1 (0.37) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3480794 | 0.87 | SMN1; SMN2 (0.34) | KMT2AMEN1ALDH1A1KDM4ECA1 | |
| SCHEMBL13021497 | 0.85 | MEN1 (0.42) | KMT2AMEN1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8397410 | 0.84 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9514033 | 0.83 | CA1 (0.34) | KMT2AMEN1ALDH1A1KDM4ECA1 | |
| SCHEMBL23636597 | 0.82 | PSEN1 (0.39) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11876393 | 0.82 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4ECA1 | |
| SCHEMBL11876401 | 0.82 | ALDH1A1 (0.41) | KMT2AMEN1ALDH1A1KDM4ECA1 | |
| SCHEMBL1336669 | 0.80 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1KDM4ECA1 | |
| SCHEMBL8773780 | 0.79 | PTGS2 (0.40) | KMT2AMEN1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274844-B1 | ULTRAVIOLET ABSORBING POLYMERS COMPRISING 2-(2'-HYDROXY 5'-ACRYLOYLOXYALKOXYPHENYL)-2H-BENZOTRIAZOLE | IOLAB CORPORATION (US) | 1991-11-06 | — | — | EP | disclosed |
| US-4716234-A | Ultraviolet absorbing polymers comprising 2-(2'-hydroxy-5'-acryloyloxyalkoxyphenyl)-2H-benzotriazole | IOLAB CORPORATION (US) | 1987-12-29 | — | — | US | disclosed |