Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.61 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367164 | 0.84 | PTPN1 (0.62) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL395494 | 0.82 | MAPT (0.56) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL26905279 | 0.81 | CYP1B1 (0.57) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL29457006 | 0.79 | PTPN1 (0.71) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL5857951 | 0.79 | PTPN1 (0.71) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL11435010 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL1448941 | 0.77 | PTPN1 (0.69) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL11713079 | 0.77 | PTPN1 (0.69) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL30375866 | 0.77 | PTPN1 (0.69) | ALDH1A1MAPTHPGDHSP90AA1HTT | |
| SCHEMBL5678914 | 0.76 | KMT2A (0.54) | ALDH1A1MAPTHPGDHSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974721-B | Method for synthesizing 2-carbonyl substituted nitrile compound through 2, 2-trifluoroethyl ketone | 平顶山学院 | 2024-07-02 | — | — | CN | claimed |
| CN-115974721-A | Method for synthesizing 2-carbonyl substituted nitrile compound through 2,2,2-trifluoroethyl ketone | 平顶山学院 | 2023-04-18 | — | — | CN | claimed |
| CN-115974721-B | Method for synthesizing 2-carbonyl substituted nitrile compound through 2, 2-trifluoroethyl ketone | 平顶山学院 | 2024-07-02 | — | — | CN | disclosed |
| CN-115974721-A | Method for synthesizing 2-carbonyl substituted nitrile compound through 2,2,2-trifluoroethyl ketone | 平顶山学院 | 2023-04-18 | — | — | CN | disclosed |
| CN-107024834-B | Compound and coloring composition | 住友化学株式会社 | 2021-11-23 | — | — | CN | disclosed |
| EP-3536692-B1 | PYRAZOLOPYRIMIDINYL INHIBITORS OF UBIQUITIN-ACTIVATING ENZYME | MILLENNIUM PHARM INC (US) | 2021-04-07 | — | — | EP | disclosed |
| EP-3536692-B1 | PYRAZOLOPYRIMIDINYL INHIBITORS OF UBIQUITIN-ACTIVATING ENZYME | MILLENNIUM PHARM INC (US) | 2021-04-07 | — | — | EP | disclosed |
| CN-107586469-B | Pigment composition, coloring composition, and coloring curable composition | 住友化学株式会社 | 2021-04-06 | — | — | CN | disclosed |
| EP-3536692-A1 | PYRAZOLOPYRIMIDINYL INHIBITORS OF UBIQUITIN-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3536692-A1 | PYRAZOLOPYRIMIDINYL INHIBITORS OF UBIQUITIN-ACTIVATING ENZYME | Millennium Pharmaceuticals, Inc. (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3173413-B1 | PYRAZOLOPYRIMIDINYL INHIBITORS OF UBIQUITIN-ACTIVATING ENZYME | MILLENNIUM PHARM INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20020143004-A1 | Allosteric adenosine receptor modulators | KING PHARMACEUTICALS RESEARCH & DEVELOPMENT, INC. | 2002-10-03 | — | — | US | disclosed |
| WO-2002074056-A2 | ALLOSTERIC ADENOSINE RECEPTOR MODULATORS | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT INC. (US) | 2002-09-26 | — | — | WO | disclosed |
| US-20010047008-A1 | Allosteric adenosine receptor modulators | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. | 2001-11-29 | — | — | US | disclosed |
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| EP-0459830-A1 | Pharmacologically active CNS compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |
| US-4017313-A | Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3933423-A | Azoic dyeing of leather | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010047008-A1 | Allosteric adenosine receptor modulators | ADORA2A, ADORA1, ADORA2B | ALDH1A1 291/4885MAPT 4793/4885HPGD 972/4885 |
| US-20020143004-A1 | Allosteric adenosine receptor modulators | ADORA2A, ADORA1, ADORA2B | ALDH1A1 328/4885MAPT 4839/4885HPGD 1035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.