⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3480747 | 0.92 | PLA2G7 (0.31) | — | |
| SCHEMBL3998872 | 0.89 | — | — | |
| SCHEMBL3480107 | 0.88 | CMA1 (0.33) | — | |
| SCHEMBL3480602 | 0.88 | TRPV4 (0.32) | — | |
| SCHEMBL3480395 | 0.87 | — | — | |
| SCHEMBL3480879 | 0.86 | TRPV4 (0.30) | — | |
| SCHEMBL3480787 | 0.81 | TRPV4 (0.31) | — | |
| SCHEMBL4551774 | 0.81 | PLA2G7 (0.34) | — | |
| SCHEMBL3480267 | 0.80 | — | — | |
| SCHEMBL3480088 | 0.80 | PTGDR2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | 92229129 QUEBEC INC. (CA) | 2010-12-16 | — | — | US | claimed |
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | 92229129 QUEBEC INC. (CA) | 2010-12-16 | — | — | US | disclosed |