SCHEMBL3480951

SCHEMBL3480951

Nc1ccc2c(c1)sc1ccc(N)cc12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.73
SMN1; SMN2 Q16637 5/20 0.73
RAB9A P51151 5/20 0.73
ALDH1A1 P00352 4/20 0.73
HPGD P15428 3/20 0.73
MMP12 P39900 1/20 0.39
GPR3 P46089 1/20 0.39
NOX4 Q9NPH5 2/20 0.38
KDM4E B2RXH2 4/20 0.36
GAA P10253 4/20 0.36
NPC1 O15118 4/20 0.36
GLA P06280 3/20 0.36
CA2 P00918 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
POLB P06746 2/20 0.36
GFER P55789 2/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31238914 1.00 MAPT (0.73) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL18965676 0.91 MAPT (0.72) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL204571 0.91 MAPT (0.78) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL30267589 0.91 MAPT (0.78) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL3887754 0.91 MAPT (0.58) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL30340804 0.91 MAPT (0.58) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL30785527 0.91 MAPT (0.78) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
Hydrochloric Acid SCHEMBL7056525 0.88 MAPT (0.75) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL23105500 0.86 MAPT (0.61) MAPTSMN1; SMN2RAB9AALDH1A1HPGD
SCHEMBL11708160 0.86 ALDH1A1 (0.56) MAPTSMN1; SMN2RAB9AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291223-B2 Epitaxial organic layered structure and method for making NITTO DENKO CORPORATION (JP) 2007-11-06 US claimed
JP-2007504305-A 2007-03-01 JP claimed
US-7166161-B2 Anisotropic film manufacturing NITTO DENKO CORPORATION (JP) 2007-01-23 US claimed
US-20050103258-A1 Epitaxial organic layered structure and method for making INSOLVENCY SERVICES GROUP, INC. 2005-05-19 US claimed
WO-2005032217-A1 EPITAXIAL ORGANIC LAYERED STRUCTURE AND METHOD FOR MAKING NITTO DENKO CORPORATION (JP) 2005-04-07 WO claimed
US-20040224182-A1 Backlight polar organic light-emitting device INSOLVENCY SERVICES GROUP, INC. 2004-11-11 US claimed
WO-2004065524-A1 ANISOTROPIC FILM MANUFACTURING NITTO DENKO CORPORATION (JP) 2004-08-05 WO claimed
WO-2004064112-A2 BACKLIGHT POLAR ORGANIC LIGHT-EMITTING DEVICE NITTO DENKO CORPORATION (JP) 2004-07-29 WO claimed
US-20040142183-A1 Anisotropic film manufacturing INSOLVENCY SERVICES GROUP, INC. 2004-07-22 US claimed
US-7742138-B2 Liquid crystal display HITACHI DISPLAYS, LTD. (JP) 2010-06-22 US disclosed
US-7291223-B2 Epitaxial organic layered structure and method for making NITTO DENKO CORPORATION (JP) 2007-11-06 US disclosed
US-7166161-B2 Anisotropic film manufacturing NITTO DENKO CORPORATION (JP) 2007-01-23 US disclosed
US-20050271833-A1 Liquid crystal display HITACHI DISPLAYS, LTD. 2005-12-08 US disclosed
US-20050103258-A1 Epitaxial organic layered structure and method for making INSOLVENCY SERVICES GROUP, INC. 2005-05-19 US disclosed
CN-1285818-A Compounds for antemortem diagnosis and in vivo imaging of alzheimer's disease and prevention of amyloid deposition UNIV PITTSBURGH (US) 2001-02-28 CN disclosed
EP-1028941-A2 COMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIVERSITY OF PITTSBURGH (US) 2000-08-23 EP disclosed
WO-1999024394-A2 COMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIVERSITY OF PITTSBURGH (US) 1999-05-20 WO disclosed
CN-1189816-A Azocompounds for the antemortem diagnosis of alzheimer's disease and in vivo imaging and prevention of amyloid depositon UNIV PITTSBURGH (US) 1998-08-05 CN disclosed
EP-0823894-A1 AZOCOMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIVERSITY OF PITTSBURGH (US) 1998-02-18 EP disclosed
WO-1996034853-A1 AZOCOMPOUNDS FOR THE ANTEMORTEM DIAGNOSIS OF ALZHEIMER'S DISEASE AND IN VIVO IMAGING AND PREVENTION OF AMYLOID DEPOSITION UNIVERSITY OF PITTSBURGH (US) 1996-11-07 WO disclosed