Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.78 |
| ▸ | RAB9A | P51151 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | HPGD | P15428 | 3/20 | 0.78 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30267589 | 1.00 | MAPT (0.78) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL30785527 | 1.00 | MAPT (0.78) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL7056525 | 0.97 | MAPT (0.75) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL18965676 | 0.95 | MAPT (0.72) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL3480951 | 0.91 | MAPT (0.73) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL31238914 | 0.91 | MAPT (0.73) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL24254893 | 0.89 | MAPT (0.64) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL2343867 | 0.89 | ALDH1A1 (1.00) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL29671009 | 0.89 | ALDH1A1 (1.00) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD | |
| SCHEMBL29671010 | 0.89 | ALDH1A1 (1.00) | MAPTSMN1; SMN2RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7331997-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-02-19 | — | — | US | claimed |
| US-20070099905-A1 | Combinations of drugs for the treatment of neoplasms | BORISY ALEXIS | 2007-05-03 | — | — | US | claimed |
| CN-1681511-A | Combinations of drugs for the treatment of neoplasms | COMBINATORX INC (US) | 2005-10-12 | — | — | CN | claimed |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-10-06 | — | — | US | claimed |
| US-20050080075-A1 | Formulations, conjugates, and combinations of drugs for the treatment of neoplasms | COMBINATORX, INC. | 2005-04-14 | — | — | US | claimed |
| US-20050054708-A1 | Combinations of drugs for the treatment of neoplasms | COMINATORX, INCORPORATED | 2005-03-10 | — | — | US | claimed |
| US-20040116407-A1 | Combinations of drugs for the treatment of neoplasms | COMBINATORX, INC. | 2004-06-17 | — | — | US | claimed |
| WO-2004006849-A2 | COMBINATIONS OF DRUGS FOR THE TREATMENT OF NEOPLASMS | COMBINATORX, INCORPORATED (US) | 2004-01-22 | — | — | WO | claimed |
| EP-0342433-A2 | Substituted dibenzothiaphenes | AMERICAN CYANAMID COMPANY (US) | 1989-11-23 | — | — | EP | claimed |
| WO-2022034907-A1 | METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN | 東ソー株式会社 | 2022-02-17 | — | — | WO | disclosed |
| US-10968392-B2 | Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer | JNC CORPORATION (JP) | 2021-04-06 | — | — | US | disclosed |
| CN-106588890-B | Antiviral compounds | 吉利德制药有限责任公司 | 2020-11-27 | — | — | CN | disclosed |
| EP-3626716-A1 | ANTIVIRAL COMPOUNDS | Gilead Pharmasset LLC (US) | 2020-03-25 | — | — | EP | disclosed |
| EP-3309157-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2019-09-04 | — | — | EP | disclosed |
| EP-0361377-A2 | Pervaporation method of separating liquid organic compound mixture through aromatic imide polymer asymmetric membrane | UBE INDUSTRIES, LTD. (JP) | 1990-04-04 | — | — | EP | disclosed |
| EP-0342433-A2 | Substituted dibenzothiaphenes | AMERICAN CYANAMID COMPANY (US) | 1989-11-23 | — | — | EP | disclosed |
| US-4314015-A | Electrophotographic sensitive materials containing disazo compounds | RICOH CO., LTD. (JP) | 1982-02-02 | — | — | US | disclosed |
| US-4299896-A | Electrophotographic sensitive materials containing a disazo pigment | RICOH CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968392-B2 | Liquid crystal aligning agent for photoalignment, liquid crystal alignment film and liquid crystal display device using it, and diamine and polymer | DDT, DCLRE1A, DVL1 | MAPT 94/4885SMN1; SMN2 3082/4885RAB9A 1320/4885 |
| US-20050217038-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, TUBB6 | MAPT 420/4885SMN1; SMN2 4772/4885RAB9A 4019/4885 |
| US-20050080075-A1 | Formulations, conjugates, and combinations of drugs for the treatment of neoplasms | ABCB1, SLCO1B3, SLCO1B1 | MAPT 790/4885SMN1; SMN2 2362/4885RAB9A 1496/4885 |
| US-20070099905-A1 | Combinations of drugs for the treatment of neoplasms | VHL, NRAS, MYC | MAPT 4349/4885SMN1; SMN2 1821/4885RAB9A 4125/4885 |
| US-20050054708-A1 | Combinations of drugs for the treatment of neoplasms | TYMP, DPYD, DHFR | MAPT 4795/4885SMN1; SMN2 611/4885RAB9A 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.