SCHEMBL3481070

SCHEMBL3481070

COc1cc(S(=O)(=O)CCOS(=O)(=O)O)c(C)cc1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.45
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
MMP13 P45452 1/20 0.35
F2 P00734 3/20 0.35
PRSS1 P07477 3/20 0.35
PRSS2 P07478 3/20 0.35
PRSS3 P35030 3/20 0.35
POLB P06746 2/20 0.35
PTAFR P25105 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
LMNA P02545 2/20 0.33
HTT P42858 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6853410 0.96 PKM (0.49) PKMALDH1A1MEN1KMT2ACA1
SCHEMBL5378130 0.90 PKM (0.46) PKMALDH1A1MEN1KMT2ACA1
SCHEMBL3481007 0.89 PKM (0.55) PKMALDH1A1CA1CA2MMP1
SCHEMBL12829691 0.87 MEN1 (0.50) ALDH1A1MEN1KMT2APOLBPTAFR
SCHEMBL11308738 0.87 PKM (0.49) PKMALDH1A1MEN1KMT2ACA1
Sulfuric Acid SCHEMBL6853414 0.87 PKM (0.48) PKMALDH1A1MEN1KMT2ACA1
SCHEMBL6883940 0.86 PKM (0.47) PKMALDH1A1CA1CA2MMP1
SCHEMBL8509967 0.85 CYP3A4 (0.35) ALDH1A1CA1CA2L3MBTL1LMNA
SCHEMBL9682404 0.85 GAA (0.45) PKMALDH1A1CA1CA2MMP1
Sulfuric Acid SCHEMBL11670357 0.84 PKM (0.46) PKMALDH1A1MEN1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
US-5463100-A Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US claimed
EP-0390826-B1 PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-19 EP claimed
EP-2861673-B1 METAL FREE REACTIVE DYES, PROCESS FOR THE PRODUCTION THEREOF AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2023-08-09 EP disclosed
EP-3752649-B1 PROCESS FOR THE SIMULTANEOUS TANNING AND DYEING OF COLLAGEN CONTAINING FIBROUS MATERIAL HUNTSMAN ADV MAT SWITZERLAND (CH) 2021-11-17 EP disclosed
CN-102199365-B NK-BB red dye special for nylon, and preparation method thereof ANHUI FENGYANG DYESTUFFS & CHEMICALS CO LTD 2014-01-29 CN disclosed
CN-101705011-B Dark blue dye for dyeing nylon TIANJIN DEKAI CHEM IND CO LTD 2013-11-13 CN disclosed
CN-101709157-B Reactive navy blue dye suitable for nylon dyeing TIANJIN DEKAI CHEM IND CO LTD 2013-11-13 CN disclosed
CN-101735658-B Reactive navy blue dye suitable for dyeing nylon and preparation method thereof TIANJIN DEKAI CHEM IND CO LTD 2013-08-14 CN disclosed
CN-102190906-B Nylon orange active dye and preparation method thereof Anhui shengyuan dye co ltd 2013-07-10 CN disclosed
CN-101817996-B Reactive navy blue dyestuff for nylon dyeing TIANJIN DEKAI CHEM IND CO LTD 2013-05-08 CN disclosed
US-4118382-A DYES FOR CELLULOSE, WOOL, SILK, POLYAMIDE, AND POLYURETHANE FIBERS BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-4118184-A Stable liquid aqueous composition of a water-soluble fiber-reactive azo dyestuff, containing a buffer substance, the dyestuff having been prepared by diazotization with a nitrite and coupling in the absence of acid HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4035350-A Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-3988310-A FIBER-REACTIVE DYES; CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed
US-3957751-A WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed