SCHEMBL3481007

SCHEMBL3481007

COc1cc(S(=O)(=O)CCOS(=O)(=O)O)c(OC)cc1N

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.55
HTR2A P28223 2/20 0.39
HTR2C P28335 1/20 0.39
HTR2B P41595 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
MMP8 P22894 1/20 0.36
MMP13 P45452 1/20 0.36
F2 P00734 3/20 0.36
PRSS1 P07477 3/20 0.36
PRSS2 P07478 3/20 0.36
PRSS3 P35030 3/20 0.36
POLB P06746 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
PTAFR P25105 2/20 0.34
GAA P10253 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6883940 0.94 PKM (0.47) PKMHTR2AHTR2CHTR2BCA1
SCHEMBL6853410 0.93 PKM (0.49) PKMHTR2AHTR2CHTR2BCA1
SCHEMBL8817851 0.90 CA2 (0.47) PKMCA1CA2MMP1MMP2
SCHEMBL5374272 0.90 PKM (0.57) PKMHTR2AHTR2CHTR2BCA1
SCHEMBL3481070 0.89 PKM (0.45) PKMHTR2AHTR2CHTR2BCA1
SCHEMBL5673840 0.89 PKM (0.45) PKMHTR2AHTR2CHTR2BCA1
SCHEMBL9776691 0.89 PKM (0.42) PKMHTR2AHTR2CHTR2BCA1
SCHEMBL9682404 0.87 GAA (0.45) PKMCA1CA2MMP1MMP2
SCHEMBL8614266 0.86 PKM (0.53) PKMHTR2AHTR2CHTR2BCA1
SCHEMBL11311830 0.86 PKM (0.39) PKMHTR2AHTR2CHTR2BCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US claimed
US-20020055619-A1 Process for preparing azo colorants CLARIANT GMBH 2002-05-09 US claimed
WO-1997025472-A1 METHOD OF PRODUCING COLOURED NATURAL OR SYNTHETIC SUBSTRATES DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1997-07-17 WO claimed
CN-1030984-C Method for preparing amino aryl-beta-sulfatoethyl sulfone HOECHST AG (DE) 1996-02-14 CN claimed
US-5463100-A Spraying a mixture of an aminoaryl beta-hydroxyethylsulfone and sulfuric acid into a hot gas stream; drying, esterification and any hydrolysis take place simultaneously; granules HOECHST AKTIENGESELLSCHAFT (DE) 1995-10-31 US claimed
EP-0390826-B1 PROCESS FOR PRODUCING AMINOARYL-BETA-SULPHATOETHYLSULPHONE COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1992-11-19 EP claimed
EP-3752649-B1 PROCESS FOR THE SIMULTANEOUS TANNING AND DYEING OF COLLAGEN CONTAINING FIBROUS MATERIAL HUNTSMAN ADV MAT SWITZERLAND (CH) 2021-11-17 EP disclosed
EP-1934293-B2 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2020-12-09 EP disclosed
CN-102292400-B The disazo dyes of fibre-active copper complexing DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2016-01-20 CN disclosed
CN-102199365-B NK-BB red dye special for nylon, and preparation method thereof ANHUI FENGYANG DYESTUFFS & CHEMICALS CO LTD 2014-01-29 CN disclosed
CN-101735658-B Reactive navy blue dye suitable for dyeing nylon and preparation method thereof TIANJIN DEKAI CHEM IND CO LTD 2013-08-14 CN disclosed
CN-102190906-B Nylon orange active dye and preparation method thereof Anhui shengyuan dye co ltd 2013-07-10 CN disclosed
CN-101812244-B Reactive dye for dyeing nylon and preparation method thereof TIANJIN DEK CHEMICAL CO LTD 2013-06-19 CN disclosed
US-4430259-A Water-soluble disazo compounds suitable as fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1984-02-07 US disclosed
US-4394310-A DIAZOTIZATION, CYCLIZATION HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-19 US disclosed
EP-0073267-A1 Copper phthalocyanine blue reactive dyes, process for their production, and their use for dyeing cellulosic fibers SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-03-09 EP disclosed
US-4341699-A Reactive red dye having both monochlorotriazinyl- and vinylsulfone-type reactive groups SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-07-27 US disclosed
US-4283196-A FIXING BY ACTION OF AN ALKALINE AGENT AMERICAN HOECHST CORPORATION (US) 1981-08-11 US disclosed
US-4271072-A FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES AMERICAN HOECHST CORPORATION (US) 1981-06-02 US disclosed
US-4252529-A AMINOPHENOL OR AMINONAPHTHOL COMPOUND WITH SUBSTITUTED FIBER-REACTIVE RADICAL HOECHST AKTIENGESELLSCHAFT (DE) 1981-02-24 US disclosed