SCHEMBL348140

SCHEMBL348140

COc1cc2nccnc2cc1OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 3/20 0.59
PDGFRA P16234 3/20 0.59
NQO2 P16083 1/20 0.50
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
EGFR P00533 2/20 0.44
PGK1 P00558 1/20 0.43
BMPR1B O00238 1/20 0.43
GAK O14976 1/20 0.43
EPHB6 O15197 1/20 0.43
RIPK2 O43353 1/20 0.43
ABL1 P00519 1/20 0.43
LCK P06239 1/20 0.43
SRC P12931 1/20 0.43
EPHA1 P21709 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22324000 0.84 PDGFRB (0.46) PDGFRBPDGFRAEGFRCCNB2CDK1
SCHEMBL4400367 0.79 PDGFRB (0.72) PDGFRBPDGFRAEGFRSRC
SCHEMBL4299023 0.75 PDGFRB (1.00) PDGFRBPDGFRANQO2ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL9379842 0.75 NPC1 (0.52) PDGFRBPDGFRAMEN1KMT2A
SCHEMBL1496287 0.74 PDGFRB (0.57) PDGFRBPDGFRAEGFRBMPR1BGAK
SCHEMBL197798 0.74 PDGFRB (0.46) PDGFRBPDGFRANQO2ALDH1A1SMN1; SMN2
Hydrochloric Acid SCHEMBL29357672 0.74 PDGFRB (0.96) PDGFRBPDGFRANQO2ALDH1A1SMN1; SMN2
Amiquinsin SCHEMBL242841 0.73 EHMT2 (0.63) PDGFRBPDGFRAEGFRBMPR1BGAK
SCHEMBL11768767 0.73 PDGFRB (0.55) PDGFRBPDGFRAEGFRBMPR1BGAK
SCHEMBL165285 0.73 PDGFRB (0.55) PDGFRBPDGFRAEGFRBMPR1BGAK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP claimed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US claimed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP claimed
CN-114524773-B Synthesis method of aryl quinoxaline compound promoted by mechanical force 浙江工业大学 2024-05-28 CN disclosed
US-11518833-B2 Composition, film, near infrared cut filter, laminate, pattern forming method, solid image pickup element, image display device, infrared sensor, and color filter FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20210139708-A1 COMPOSITION, FILM, NEAR INFRARED CUT FILTER, LAMINATE, PATTERN FORMING METHOD, SOLID IMAGE PICKUP ELEMENT, IMAGE DISPLAY DEVICE, INFRARED SENSOR, AND COLOR FILTER FUJIFILM CORPORATION (JP) 2021-05-13 US disclosed
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
CN-101001900-B Process for producing aromatic compound polymer SUMITOMO CHEMICAL CO 2011-04-20 CN disclosed
CN-101914111-A The preparation method of aromatic compound polymer SUMITOMO CHEMICAL CO 2010-12-15 CN disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
CN-101001900-A Process for producing aromatic compound polymer SUMITOMO CHEMICAL CO (JP) 2007-07-18 CN disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed
EP-0014688-B1 PROCESS FOR THE TREATMENT OF SILVER DYE-BLEACHING MATERIALS, AQUEOUS PREPARATION THEREFOR, CONCENTRATE AND PROCESS FOR MAKING THE PREPARATION CIBA-GEIGY AG (CH) 1983-03-23 EP disclosed
US-4304846-A USING MIXTURES OF A 1,4- OR 1,2-DIAZINE AS BLEACHING CATALYSTS; PREFERENTIAL REDOX POTENTIALS CIBA-GEIGY AG (CH) 1981-12-08 US disclosed
EP-0014688-A2 Process for the treatment of silver dye-bleaching materials, aqueous preparation therefor, concentrate and process for making the preparation CIBA-GEIGY AG (CH) 1980-08-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR PDGFRB 599/4885PDGFRA 170/4885NQO2 1700/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR PDGFRB 576/4885PDGFRA 162/4885NQO2 1664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.