SCHEMBL3481634

SCHEMBL3481634

Clc1ccc(Cl)c(Sc2ccccn2)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 3/20 0.62
L3MBTL1 Q9Y468 1/20 0.59
POLB P06746 1/20 0.58
MAPT P10636 4/20 0.50
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
HPGD P15428 2/20 0.50
USP2 O75604 1/20 0.50
GAA P10253 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
EHMT2 Q96KQ7 1/20 0.44
EHMT1 Q9H9B1 1/20 0.44
APOBEC3G Q9HC16 1/20 0.44
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
RHEB Q15382 1/20 0.41
MAPK14 Q16539 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4682214 0.76 L3MBTL1 (0.96) PDE7AL3MBTL1POLBMAPTALDH1A1
SCHEMBL11134251 0.75 EHMT2 (0.61) PDE7AL3MBTL1POLBMAPTALDH1A1
SCHEMBL30548750 0.75 EHMT2 (0.61) PDE7AL3MBTL1POLBMAPTALDH1A1
SCHEMBL7268486 0.74 HPGD (0.58) POLBMAPTALDH1A1MEN1KMT2A
SCHEMBL2977936 0.73 PDE7A (0.59) PDE7AL3MBTL1POLBMAPTALDH1A1
SCHEMBL11864763 0.73 L3MBTL1 (0.64) PDE7AL3MBTL1POLBMAPTALDH1A1
SCHEMBL7696122 0.72 HPGD (0.43) PDE7APOLBMAPTALDH1A1HPGD
SCHEMBL301719 0.72 EHMT2 (0.70) PDE7AL3MBTL1POLBMAPTALDH1A1
SCHEMBL9510742 0.72 MEN1 (0.53) PDE7AL3MBTL1ALDH1A1MEN1KMT2A
SCHEMBL192475 0.70 L3MBTL1 (0.61) PDE7AL3MBTL1POLBMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8273499-B2 Membrane-electrode assembly for solid polymer electrolyte fuel cell HONDA MOTOR CO., LTD. (JP) 2012-09-25 US disclosed
US-20100062311-A1 MEMBRANE-ELECTRODE ASSEMBLY FOR SOLID POLYMER ELECTROLYTE FUEL CELL HONDA MOTOR CO., LTD. (JP) 2010-03-11 US disclosed