⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770207 | 0.88 | LMNA (0.30) | — | |
| SCHEMBL7014044 | 0.84 | TSHR (0.33) | — | |
| SCHEMBL3481656 | 0.84 | — | — | |
| SCHEMBL26113601 | 0.82 | TSHR (0.38) | — | |
| SCHEMBL26113457 | 0.82 | TSHR (0.38) | — | |
| SCHEMBL2333576 | 0.82 | — | — | |
| SCHEMBL3482190 | 0.79 | — | — | |
| SCHEMBL17233353 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL8374429 | 0.75 | TSHR (0.32) | — | |
| SCHEMBL5154689 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106566855-A | Nucleic acid amplification using reversibly modified oligonucleotide | 毕万里 | 2017-04-19 | — | — | CN | claimed |
| CN-113677364-B | Pharmaceutical compositions comprising anti-191P 4D12 antibody drug conjugates and methods of use thereof | 艾更斯司股份有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-106563128-B | Use of auristatin-based antibody drug conjugates and mTOR-binding inhibitors in the manufacture of a medicament for the treatment of cancer | 西雅图遗传学公司 | 2020-05-22 | — | — | CN | disclosed |
| CN-105567717-B | It is incorporated into the antibody drug conjugates (ADC) of 191P4D12 albumen | Algens Co.,Ltd. (US) | 2019-10-29 | — | — | CN | disclosed |
| CN-109963833-A | It is used to prepare mono-protected α, ω-Diaminoalkane method | 斯索恩生物制药有限公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-105722534-B | In conjunction with the antibody drug conjugates (ADC) of CD37 albumen | 艾更斯司股份有限公司 | 2019-05-31 | — | — | CN | disclosed |
| CN-105246866-B | The method of synthesis ingenol and its intermediate | 利奥实验室有限公司 | 2017-06-16 | — | — | CN | disclosed |
| CN-106566855-A | Nucleic acid amplification using reversibly modified oligonucleotide | 毕万里 | 2017-04-19 | — | — | CN | disclosed |
| US-9546237-B2 | Stabilization of polymers that contain a hydrolyzable functionality | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| CN-106061965-A | Novel pyrazolyl-heteroarylamides as pesticides | 拜耳动物保健有限责任公司 | 2016-10-26 | — | — | CN | disclosed |
| CN-101175486-A | Drug delivery system with chitosan and polyethylene glycol nanoparticles as bioactive molecules | ADVANCED IN VITRO CELL TECH (ES) | 2008-05-07 | — | — | CN | disclosed |
| CN-101039701-A | Prodrugs and codrug comprising a biocleavable disulfide linker | NICHOLAS PIRAMAL INDIA LTD (IN) | 2007-09-19 | — | — | CN | disclosed |
| US-7270916-B2 | Recording medium | KABUSHIKI KAISHA TOSHIBA (JP) | 2007-09-18 | — | — | US | disclosed |
| US-6899999-B2 | Method of manufacturing composite member, photosensitive composition, porous base material, insulating body and composite member | KABUSHIKI KAISHA TOSHIBA (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20050026079-A1 | Recording medium | PARALLEL WIRELESS, INC. | 2005-02-03 | — | — | US | disclosed |
| CN-1568190-A | Combination therapy comprising glucose reabsorption inhibitor and PPAR modulator | ORTHO MCNEIL PHARM INC (US) | 2005-01-19 | — | — | CN | disclosed |
| US-20030022102-A1 | Method of manufacturing composite member, photosensitive composition, porous base material, insulating body and composite member | KABUSHIKI KAISHA TOSHIBA (JP) | 2003-01-30 | — | — | US | disclosed |
| CN-1304306-A | Method for inhibiting MRP1 | LILLY CO ELI (US) | 2001-07-18 | — | — | CN | disclosed |
| CN-1254280-A | A regioselective alkylation process for preparing substituted benzo [b] thiophenes | LILLY CO ELI (US) | 2000-05-24 | — | — | CN | disclosed |
| CN-1252717-A | Intermediate and method for preparing benzo [ b ] thiophene | LILLY CO ELI (US) | 2000-05-10 | — | — | CN | disclosed |