SCHEMBL3481745

SCHEMBL3481745

C[Si](C)(C)c1ccc(-c2cc(-c3ccc([Si](C)(C)C)cc3)c(-c3ccc([Si](C)(C)C)cc3)cc2-c2ccc([Si](C)(C)C)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
SCN5A Q14524 1/20 0.35
USP7 Q93009 1/20 0.33
PTAFR P25105 1/20 0.33
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL756025 0.84 NR1H2 (0.32) NR1H2NR1H3SCN5A
SCHEMBL10997473 0.82 NR1H2 (0.44) NR1H2NR1H3SCN5APTAFRACHE
SCHEMBL15453339 0.81 PTAFR (0.42) NR1H2NR1H3SCN5APTAFR
SCHEMBL15453485 0.80 PTGS2 (0.37) PTAFR
SCHEMBL14553136 0.80 ESR1 (0.41) NR1H2NR1H3SCN5APTAFRACHE
SCHEMBL586534 0.78 NR1H2 (0.50) NR1H2NR1H3SCN5AACHE
SCHEMBL13251131 0.77
SCHEMBL13251017 0.77
SCHEMBL13250961 0.77 CA12 (0.40)
SCHEMBL13251059 0.77 CA12 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2264040-A1 Proton-conducting organic materials Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2010-12-22 EP disclosed