Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117351 | 0.92 | ADRB1 (0.67) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2115040 | 0.92 | ADRB1 (0.61) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2116252 | 0.92 | SIGMAR1 (0.65) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2113938 | 0.89 | ADRB1 (0.80) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2115634 | 0.89 | ADRB1 (0.62) | ADRB1HTR2AHTR2BSIGMAR1HTR1A | |
| SCHEMBL2115966 | 0.89 | ADRB1 (0.62) | ADRB1HTR2AHTR2BSIGMAR1HTR1A | |
| SCHEMBL2114175 | 0.88 | ADRB1 (0.62) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL3407135 | 0.87 | ADRB1 (0.76) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2114578 | 0.87 | ADRB1 (0.76) | ADRB1HTR2AHTR2BSIGMAR1 | |
| SCHEMBL2115305 | 0.87 | ADRB1 (0.69) | ADRB1HTR2AHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150550-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK Holdings Co., Ltd. (KR) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008140197-A1 | NOVEL CARBAMOYLOXY ARYL ALKAN ARYLPIPERAZINE COMPOUND, PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUND AND METHOD FOR TREATING PAIN, ANXIETY AND DEPRESSION BY ADMINISTERING THE COMPOUND | SK HOLDINGS CO., LTD. (KR) | 2008-11-20 | — | — | WO | disclosed |