SCHEMBL3482368

SCHEMBL3482368

C=C[Si](C=C)(CCC)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
TSHR P16473 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8084574 0.86 KCNH2 (0.36) ALDH1A1TSHRMAPT
SCHEMBL23514189 0.83 TSHR (0.33) ALDH1A1TSHRTP53MAPTL3MBTL1
SCHEMBL27798257 0.79 ALDH1A1 (0.31) ALDH1A1TSHRL3MBTL1
SCHEMBL23388794 0.79 TDP1 (0.33) ALDH1A1TSHRMAPTL3MBTL1
SCHEMBL3481647 0.76
SCHEMBL15302038 0.76 NR1H2 (0.30)
SCHEMBL2292618 0.76 MAPT (0.33) MAPTGAA
SCHEMBL28218923 0.75 TP53 (0.38) ALDH1A1TSHRTP53MAPTKDM4E
SCHEMBL27473726 0.74 LOXL2 (0.33) ALDH1A1TSHRL3MBTL1
SCHEMBL1271104 0.74 ALDH1A1 (0.33) ALDH1A1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057239-B1 BRANCHED POLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2015-03-04 EP disclosed
EP-2057238-B1 COMPOSITION CONTAINING ANTI-MISTING COMPONENT MOMENTIVE PERFORMANCE MAT INC (US) 2012-10-10 EP disclosed
CN-101535428-B Composition containing anti-misting component MOMENTIVE PERFORMANCE MAT INC 2012-10-10 CN disclosed
CN-101535427-B Branched polysiloxane composition MOMENTIVE PERFORMANCE MAT INC 2012-07-04 CN disclosed
US-7649071-B2 Branched polysiloxane composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-01-19 US disclosed
CN-101535427-A Branched polysiloxane composition MOMENTIVE PERFORMANCE MAT INC (US) 2009-09-16 CN disclosed
CN-101535428-A Composition containing anti-misting component MOMENTIVE PERFORMANCE MAT INC (US) 2009-09-16 CN disclosed
US-7560167-B2 branched polysiloxane component; paper release coating; high-speed coating processes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2009-07-14 US disclosed
EP-2057239-A2 BRANCHED POLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2009-05-13 EP disclosed
EP-2057238-A2 COMPOSITION CONTAINING ANTI-MISTING COMPONENT Momentive Performance Materials Inc. (US) 2009-05-13 EP disclosed
WO-2008027497-A2 BRANCHED POLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-03-06 WO disclosed
US-20080058479-A1 Composition containing anti-misting component GENERAL ELECTRIC COMPANY (US) 2008-03-06 US disclosed
US-20080058491-A1 Branched polysiloxane composition GENERAL ELECTRIC COMPANY (US) 2008-03-06 US disclosed
WO-2008027494-A2 COMPOSITION CONTAINING ANTI-MISTING COMPONENT MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2008-03-06 WO disclosed