SCHEMBL3482369

SCHEMBL3482369

CCC(C)CN1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.52
ALDH1A1 P00352 3/20 0.52
BLM P54132 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
GMNN O75496 1/20 0.52
THPO P40225 1/20 0.52
PMP22 Q01453 1/20 0.52
FAAH O00519 5/20 0.42
PTGS1 P23219 4/20 0.42
PTGS2 P35354 4/20 0.42
HPGD P15428 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
WRN Q14191 1/20 0.39
HIF1A Q16665 1/20 0.39
HSP90AA1 P07900 1/20 0.39
TLR9 Q9NR96 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17924830 0.80 MGLL (0.44) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL3677233 0.79 MGLL (0.50) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL17924865 0.78 MGLL (0.48) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL153302 0.78 MGLL (0.52) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL29148404 0.77 MGLL (0.52) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL17924922 0.77 MGLL (0.41) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL14864015 0.77 MGLL (0.41) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL19019642 0.77 MGLL (0.56) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL20378716 0.77 MGLL (0.42) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL19019377 0.77 MGLL (0.56) MGLLALDH1A1BLMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230323434-A1 GENERATING CAPTURE PROBES FOR SPATIAL ANALYSIS 10X GENOMICS, INC. 2023-10-12 US disclosed
US-20180015178-A1 ANTI-DLL3 ANTIBODY DRUG CONJUGATES AND METHODS OF USE ABBVIE STEMCENTRX LLC (US) 2018-01-18 US disclosed
US-9814777-B2 Targeting lipids ARBUTUS BIOPHARMA CORPORATION (CA) 2017-11-14 US disclosed
CN-107112541-A Binder composition for lithium ion secondary battery negative electrode, slurry composition for lithium ion secondary battery negative electrode using same, lithium ion secondary battery negative electrode, and lithium ion secondary battery 株式会社可乐丽 2017-08-29 CN disclosed
US-20160209743-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR FORMING MEMBER HAVING CURVED SHAPE, PHOTOSENSITIVE RESIN FILM FOR FORMING MEMBER HAVING CURVED SHAPE USING SAID COMPOSITION, AND LENS MEMBER MANUFACTRED USING SAID COMPOSITION OR SAID FILM HITACHI CHEMICAL COMPANY, LTD. (JP) 2016-07-21 US disclosed
US-8420764-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2013-04-16 US disclosed
CN-101583908-B Photosensitive resin composition, cured photosensitive resin product, photosensitive resin film, cured photosensitive resin film product, and optical waveguide produced by using those products HITACHI CHEMICAL CO LTD 2012-12-26 CN disclosed
US-8236917-B2 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2012-08-07 US disclosed
US-20120178894-A1 COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER INAGAKI JYUN-ICHI (JP) 2012-07-12 US disclosed
US-20100240855-A1 Compound having silsesquioxane skeleton and its polymer JNC CORPORATION (JP) 2010-09-23 US disclosed
US-7705105-B2 A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; CHISSO PETROCHEMICAL CORPORATION (JP) 2010-04-27 US disclosed
US-20070190344-A1 Verification of translation JNC CORPORATION (JP) 2007-08-16 US disclosed
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer CHISSO CORPORATION (JP) 2005-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180015178-A1 ANTI-DLL3 ANTIBODY DRUG CONJUGATES AND METHODS OF USE DLK1, DYNLL1, DYNLL2 MGLL 3261/4885ALDH1A1 1990/4885BLM 4300/4885
US-20050009982-A1 Compound having silsesquioxane skeleton and its polymer C1S, H1-4, H1-0 MGLL 4700/4885ALDH1A1 1780/4885BLM 3096/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.