SCHEMBL29148404

SCHEMBL29148404

CCC(N)CN1C(=O)C=CC1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 12/20 0.52
ALDH1A1 P00352 3/20 0.52
BLM P54132 2/20 0.52
LMNA P02545 2/20 0.52
MAPT P10636 2/20 0.52
NPSR1 Q6W5P4 2/20 0.52
GMNN O75496 1/20 0.52
THPO P40225 1/20 0.52
PMP22 Q01453 1/20 0.52
HPGD P15428 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
WRN Q14191 1/20 0.44
HIF1A Q16665 1/20 0.44
GSK3A P49840 5/20 0.42
GSK3B P49841 5/20 0.42
FAAH O00519 5/20 0.42
PTGS1 P23219 4/20 0.42
PTGS2 P35354 4/20 0.42
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14578260 0.84 MGLL (0.42) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL2480171 0.79 MGLL (0.48) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL3482369 0.77 MGLL (0.52) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL17924881 0.76 MGLL (0.50) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL14199491 0.75 MGLL (0.45) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL4593870 0.74 MGLL (0.48) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL28787032 0.74 MGLL (0.39) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL153302 0.73 MGLL (0.52) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL10107073 0.73 MGLL (0.46) MGLLALDH1A1BLMLMNAMAPT
SCHEMBL5081934 0.73 MGLL (0.46) MGLLALDH1A1BLMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486997-A Long-acting unsaturated fatty acid chain-GLP-1 receptor agonist polypeptide and preparation method thereof 大连理工大学 2024-02-02 CN claimed
CN-117486997-A Long-acting unsaturated fatty acid chain-GLP-1 receptor agonist polypeptide and preparation method thereof 大连理工大学 2024-02-02 CN disclosed