Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.89 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.77 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.77 |
| ▸ | MAOB | P27338 | 1/20 | 0.69 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.63 |
| ▸ | TTR | P02766 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | GMNN | O75496 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL573377 | 1.00 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL9860306 | 1.00 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylethyl Fumarate SCHEMBL573376 | 0.94 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylethyl Fumarate SCHEMBL27750209 | 0.94 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylethyl Fumarate SCHEMBL573379 | 0.94 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL25623741 | 0.91 | HCAR2 (0.76) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL27735855 | 0.91 | HCAR2 (0.76) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL7268059 | 0.91 | HCAR2 (0.76) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL23343675 | 0.91 | HCAR2 (0.75) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL29839413 | 0.90 | HCAR2 (0.73) | HCAR2AKR1B10AKR1B1MAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346341-A | Improvements in or related to organic compoounds | GIVAUDAN SA (CH) | 2009-01-14 | — | — | CN | claimed |
| EP-0233299-B1 | OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | claimed |
| US-4855374-A | Optical resin from diallyl esters | NIPPON OIL AND FATS CO., LTD. (JP) | 1989-08-08 | — | — | US | claimed |
| EP-0233299-A1 | Optical resin and process for preparing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-08-26 | — | — | EP | claimed |
| US-8420764-B2 | Compound having silsesquioxane skeleton and its polymer | JNC CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-20120178894-A1 | COMPOUND HAVING SILSESQUIOXANE SKELETON AND ITS POLYMER | INAGAKI JYUN-ICHI (JP) | 2012-07-12 | — | — | US | disclosed |
| CN-102372633-A | Preparation method of antiseptic mono-benzyl-methyl fumarate | UNIV JIANGSU | 2012-03-14 | — | — | CN | disclosed |
| CN-102372633-A | Preparation method of antiseptic mono-benzyl-methyl fumarate | UNIV JIANGSU | 2012-03-14 | — | — | CN | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| CN-101346341-A | Improvements in or related to organic compoounds | GIVAUDAN SA (CH) | 2009-01-14 | — | — | CN | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-0233299-B1 | OPTICAL RESIN AND PROCESS FOR PREPARING THE SAME | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4855374-A | Optical resin from diallyl esters | NIPPON OIL AND FATS CO., LTD. (JP) | 1989-08-08 | — | — | US | disclosed |
| EP-0233299-A1 | Optical resin and process for preparing the same | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1987-08-26 | — | — | EP | disclosed |
| EP-0017927-B1 | PROCESS FOR PREPARING PHOTOPOLYMERIZED ELASTOMERIC PRINTING PLATES NOT DISPLAYING SURFACE STICKINESS | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-09-19 | — | — | EP | disclosed |
| US-4468453-A | Dry process for forming an image | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4266005-A | Photosensitive elastomeric composition | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-05-05 | — | — | US | disclosed |
| EP-0017927-A2 | Process for preparing photopolymerized elastomeric printing plates not displaying surface stickiness | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1980-10-29 | — | — | EP | disclosed |
| US-4197130-A | Photosensitive elastomeric composition and element | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | HCAR2 2928/4885AKR1B10 2310/4885AKR1B1 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.