Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 1.00 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.58 |
| ▸ | TTR | P02766 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylethyl Fumarate SCHEMBL27750209 | 1.00 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylethyl Fumarate SCHEMBL573376 | 1.00 | HCAR2 (1.00) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL3482701 | 0.94 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL573377 | 0.94 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL9860306 | 0.94 | HCAR2 (0.89) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylpropyl Fumarate SCHEMBL27216278 | 0.90 | HCAR2 (0.81) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylpropyl Fumarate SCHEMBL3482832 | 0.90 | HCAR2 (0.81) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Phenylpropyl Fumarate SCHEMBL3482828 | 0.90 | HCAR2 (0.81) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| SCHEMBL28500283 | 0.87 | HCAR2 (0.77) | HCAR2AKR1B10AKR1B1MAOBALOX5 | |
| Hydrochloric Acid SCHEMBL27349461 | 0.87 | HCAR2 (0.77) | HCAR2AKR1B10AKR1B1MAOBALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040630-B2 | Graft copolymers of polyfarnesenes with condensation polymers | Amyris, Inc. (US) | 2015-05-26 | — | — | US | claimed |
| EP-2601229-B1 | GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS | AMYRIS INC (US) | 2013-10-16 | — | — | EP | claimed |
| EP-2601229-A1 | GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS | Amyris, Inc. (US) | 2013-06-12 | — | — | EP | claimed |
| US-20130123379-A1 | GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS | Amyris, Inc. (US) | 2013-05-16 | — | — | US | claimed |
| WO-2012018682-A1 | GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS | Amyris, Inc. (US) | 2012-02-09 | — | — | WO | claimed |
| EP-2817342-B1 | POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE | AMYRIS INC (US) | 2016-05-25 | — | — | EP | disclosed |
| US-9040630-B2 | Graft copolymers of polyfarnesenes with condensation polymers | Amyris, Inc. (US) | 2015-05-26 | — | — | US | disclosed |
| US-20150025193-A1 | POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE | Amyris, Inc. (US) | 2015-01-22 | — | — | US | disclosed |
| EP-2817342-A1 | POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE | Amyris, Inc. (US) | 2014-12-31 | — | — | EP | disclosed |
| US-8592543-B2 | Polyfarnesenes | EUAGORE, LLC | 2013-11-26 | — | — | US | disclosed |
| EP-2601229-B1 | GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS | AMYRIS INC (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2013126129-A1 | POLYMERIZATION OF COMPOSITIONS COMPRISING A FARNESENE | Amyris, Inc. (US) | 2013-08-29 | — | — | WO | disclosed |
| WO-2012018682-A1 | GRAFT COPOLYMERS OF POLYFARNESENES WITH CONDENSATION POLYMERS | Amyris, Inc. (US) | 2012-02-09 | — | — | WO | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| US-4654401-A | SOLVENT RESISTANCE, HIGH IMPACT STRENGTH MOLDING MATERIAL | GENERAL ELECTRIC COMPANY (US) | 1987-03-31 | — | — | US | disclosed |
| US-4632962-A | USING IN MAKING MODIFIED POLYESTERS, POLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 1986-12-30 | — | — | US | disclosed |
| EP-0186060-A2 | Hydroxyl group graft modified polyolefins | GENERAL ELECTRIC COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| US-4147740-A | UNSATURATED ANHYDRIDE, HIGH IMPACT BLENDS | GENERAL ELECTRIC COMPANY (US) | 1979-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | HCAR2 2928/4885AKR1B10 2310/4885AKR1B1 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.