SCHEMBL348291

SCHEMBL348291

COc1ccc(N(c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.71
RELA Q04206 1/20 0.56
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 4/20 0.46
TP53 P04637 1/20 0.46
SLC2A1 P11166 1/20 0.45
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL172190 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL12545287 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL10065624 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL19958553 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL23921596 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL10025025 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL12374368 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL2623449 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL12376869 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL134330 0.94 ACHE (0.62) ACHERELACA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448925-B1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORP (JP) 2017-12-06 EP disclosed
EP-2448925-B1 EMISSIVE ARYL-HETEROARYL COMPOUNDS NITTO DENKO CORP (JP) 2017-12-06 EP disclosed
US-9343684-B2 Substituted bisaryloxybiphenyl compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-17 US disclosed
US-9343684-B2 Substituted bisaryloxybiphenyl compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-17 US disclosed
US-9343684-B2 Substituted bisaryloxybiphenyl compounds for use in light-emitting devices NITTO DENKO CORPORATION (JP) 2016-05-17 US disclosed
US-20150028262-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2015-01-29 US disclosed
US-8927121-B2 Emissive aryl-heteroaryl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8927121-B2 Emissive aryl-heteroaryl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8927121-B2 Emissive aryl-heteroaryl compounds NITTO DENKO CORPORATION (JP) 2015-01-06 US disclosed
US-8895675-B2 Block copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-11-25 US disclosed
US-7378205-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2008-05-27 US disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7241543-B2 Image forming method, a photoreceptor used for the apparatus, and an image forming unit KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-10 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-7238457-B2 Electrophotographic photoreceptor KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2007-07-03 US disclosed
US-20070054209-A1 Electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2007-03-08 US disclosed
US-20070054209-A1 Electrophotographic photoconductor KYOCERA MITA CORPORATION (JP) 2007-03-08 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed
US-7175954-B2 Electrophotographic photoreceptor KONICA MINOLTA HOLDINGS, INC. (JP) 2007-02-13 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed