SCHEMBL172190

SCHEMBL172190

COc1ccc(N(c2ccc(C)cc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.71
RELA Q04206 1/20 0.56
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
KMT2A Q03164 1/20 0.47
LMNA P02545 4/20 0.46
TP53 P04637 1/20 0.46
SLC2A1 P11166 1/20 0.45
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348291 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL12545287 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL10065624 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL19958553 1.00 ACHE (0.71) ACHERELACA1CA2CA7
SCHEMBL23921596 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL10025025 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL12374368 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL2623449 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL12376869 0.94 ACHE (0.62) ACHERELACA1CA2CA7
SCHEMBL134330 0.94 ACHE (0.62) ACHERELACA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230165978-A1 Composition and A Method For Diagnosing And Treating Bacterial Infection Hong Kong Centre for Cerebro-Cardiovascular Health Engineering Limited (HK) 2023-06-01 US disclosed
US-20230165978-A1 Composition and A Method For Diagnosing And Treating Bacterial Infection Hong Kong Centre for Cerebro-Cardiovascular Health Engineering Limited (HK) 2023-06-01 US disclosed
US-11370963-B2 Electrochromic compound, electrochromic composition, and electrochromic element RICOH COMPANY, LTD. (JP) 2022-06-28 US disclosed
US-20220145173-A1 FLUORESCENT COMPOUNDS AND APPLICATION THEREOF THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) 2022-05-12 US disclosed
US-20210296586-A1 THERMALLY ACTIVATED DELAYED FLOURESCENCE (TADF) MATERIAL, SYNTHESIZING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE Wuhan China Star Optoelectronics Semiconductor Display Technology Ltd. (CN) 2021-09-23 US disclosed
US-20210198564-A1 ELECTROCHROMIC COMPOUND, ELECTROCHROMIC COMPOSITION, AND ELECTROCHROMIC ELEMENT RICOH COMPANY, LTD. (JP) 2021-07-01 US disclosed
US-10975296-B2 Electrochromic compound, electrochromic composition, and electrochromic element RICOH COMPANY, LTD. (JP) 2021-04-13 US disclosed
US-20200343454-A1 LIGHT THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) MATERIAL, PREPARING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (IL) 2020-10-29 US disclosed
US-10444588-B2 Electrochromic element, optical filter, lens unit, imaging apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2019-10-15 US disclosed
EP-2596509-B1 DYE SOLAR CELL WITH IMPROVED STABILITY BASF SE (DE) 2019-06-19 EP disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-20100168444-A1 DIINDENOTHIOPHENE DERIVATIVES AND USE THEREOF ETERNAL CHEMICAL CO., LTD. (TW) 2010-07-01 US disclosed
US-7524991-B2 Organic electroluminescent devices, aminostyrylnaphthalene compounds and synthesis intermediates thereof, and production processes of the same SONY CORPORATION (JP) 2009-04-28 US disclosed
US-7524991-B2 Organic electroluminescent devices, aminostyrylnaphthalene compounds and synthesis intermediates thereof, and production processes of the same SONY CORPORATION (JP) 2009-04-28 US disclosed
US-7507840-B2 Acceptor compounds useful for making hyperpolarizable organic chromophores UNIVERSITY OF WASHINGTON (US) 2009-03-24 US disclosed
US-7402344-B2 Organic electroluminescent devices and aminostyrylnaphthalene compounds SONY CORPORATION (JP) 2008-07-22 US disclosed
US-7402344-B2 Organic electroluminescent devices and aminostyrylnaphthalene compounds SONY CORPORATION (JP) 2008-07-22 US disclosed
US-20080051607-A1 ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME SONY CORPORATION (JP) 2008-02-28 US disclosed
US-20080051607-A1 ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME SONY CORPORATION (JP) 2008-02-28 US disclosed
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165978-A1 Composition and A Method For Diagnosing And Treating Bacterial Infection NOD2, PYCARD, NOD1 ACHE 891/4885RELA 97/4885CA1 3392/4885
US-20080051607-A1 ORGANIC ELECTROLUMINESCENT DEVICES, AMINOSTYRLNAPHTHALENE COMPOUNDS AND SYNTHESIS INTERMEDIATES THEREOF, AND PRODUCTION PROCESSES OF THE SAME ASNS, RPS24, L1CAM ACHE 555/4885RELA 1210/4885CA1 3997/4885
US-20210296586-A1 THERMALLY ACTIVATED DELAYED FLOURESCENCE (TADF) MATERIAL, SYNTHESIZING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE TEAD3, NUTF2, TEAD1 ACHE 807/4885RELA 226/4885CA1 2676/4885
US-10975296-B2 Electrochromic compound, electrochromic composition, and electrochromic element RER1, RPS6, KAT6B ACHE 2087/4885RELA 3587/4885CA1 1391/4885
US-20200343454-A1 LIGHT THERMALLY ACTIVATED DELAYED FLUORESCENCE (TADF) MATERIAL, PREPARING METHOD THEREOF, AND ELECTROLUMINESCENT DEVICE ADGRF1, ADORA1, HTR1F ACHE 1637/4885RELA 1103/4885CA1 3132/4885
US-20100168444-A1 DIINDENOTHIOPHENE DERIVATIVES AND USE THEREOF CCND3, C1S, CCND1 ACHE 3907/4885RELA 1523/4885CA1 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.