Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 1.00 |
| ▸ | FAAH | O00519 | 4/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18661434 | 0.86 | MGLL (0.75) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL31664393 | 0.85 | MGLL (0.73) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL1683222 | 0.85 | MGLL (0.73) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL19508523 | 0.81 | MGLL (0.69) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL18469620 | 0.81 | MGLL (0.69) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL17208730 | 0.81 | MGLL (0.69) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL18814236 | 0.81 | MGLL (0.68) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL19512034 | 0.80 | MGLL (0.67) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL7101837 | 0.80 | MGLL (0.67) | MGLLFAAHHSP90AA1ALDH1A1PKM | |
| SCHEMBL24452700 | 0.80 | MGLL (0.66) | MGLLFAAHHSP90AA1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724154-A | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-01-24 | — | — | CN | claimed |
| CN-110724154-B | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | disclosed |
| CN-110724154-A | Polysubstituted pyrrolo [3,4-d ] isoxazole derivative and synthetic method thereof | 湖北科技学院 | 2020-01-24 | — | — | CN | disclosed |
| US-20190125882-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2019-05-02 | — | — | US | disclosed |
| US-10256449-B2 | Porous membrane separator for secondary battery, method for producing the same, and secondary battery | ZEON CORPORATION (JP) | 2019-04-09 | — | — | US | disclosed |
| CN-105384865-B | Optical resin material, the manufacturing method of the optical resin material, the optical resin component containing the material and the polarizing film containing the component | 小池康博 | 2019-02-19 | — | — | CN | disclosed |
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2019-01-15 | — | — | US | disclosed |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2018-04-26 | — | — | US | disclosed |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE | 2018-04-26 | — | — | US | disclosed |
| US-9867883-B2 | Isatoic anhydride derivatives and applications thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHARLOTTE (US) | 2018-01-16 | — | — | US | disclosed |
| US-7705105-B2 | A cyclic polymer of silsesquioxane skeleton with side chains formed byhydrosilation of an unsaturated end group containing an active polymerfunctional group; polyimidesiloxane copolymers; polyestersiloxane copolymers; high molecular weight; thin films; strength; heat resistance;waterproofing; | CHISSO PETROCHEMICAL CORPORATION (JP) | 2010-04-27 | — | — | US | disclosed |
| CN-100504541-C | Liquid crystal display device and polarizing disc combination therefor | SUMITOMO CHEMICAL CO (JP) | 2009-06-24 | — | — | CN | disclosed |
| US-20070190344-A1 | Verification of translation | JNC CORPORATION (JP) | 2007-08-16 | — | — | US | disclosed |
| CN-1811555-A | Liquid crystal display device and polarizing disc combination therefor | SUMIKA PLASTECH CO LTD (JP) | 2006-08-02 | — | — | CN | disclosed |
| US-7018697-B2 | Optical recording medium | TDK CORPORATION (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | CHISSO CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |
| US-20040241378-A1 | A substrate; and a light transmitting layer having a thickness smaller than that of the substrate where the substrate is a copolymer of an N-phenyl maleimide, an N-alkylmaleimide, and an olefin such as isobutene; nonwarping | TDK CORPORATION (JP) | 2004-12-02 | — | — | US | disclosed |
| EP-0348906-B1 | HEAT-RESISTANT RESIN COMPOSITION | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-4994515-A | Resin of styrene and unsaturated imide, high impact thermoplastic, bromine-containing reaction product, silicon resin or compound | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0348906-A1 | Heat-resistant resin composition | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1990-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10179175-B2 | Isatoic anhydride derivatives and applications thereof | AASDHPPT, CA13, CA12 | MGLL 4080/4885FAAH 380/4885HSP90AA1 2859/4885 |
| US-20190125882-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | MGLL 4080/4885FAAH 380/4885HSP90AA1 2859/4885 |
| US-20180110862-A1 | ISATOIC ANHYDRIDE DERIVATIVES AND APPLICATIONS THEREOF | AASDHPPT, CA13, CA12 | MGLL 4080/4885FAAH 380/4885HSP90AA1 2859/4885 |
| US-20050009982-A1 | Compound having silsesquioxane skeleton and its polymer | C1S, H1-4, H1-0 | MGLL 4700/4885FAAH 4471/4885HSP90AA1 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.