⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1959420 | 0.78 | — | — | |
| SCHEMBL575235 | 0.76 | MAPK1 (0.46) | — | |
| SCHEMBL3819639 | 0.75 | CYP1A2 (0.32) | — | |
| SCHEMBL21735 | 0.75 | TSHR (0.48) | — | |
| Water SCHEMBL28104416 | 0.75 | TSHR (0.48) | — | |
| SCHEMBL1121775 | 0.75 | ESR1 (0.46) | — | |
| SCHEMBL27666552 | 0.75 | — | — | |
| SCHEMBL7737041 | 0.73 | RIPK1 (0.37) | — | |
| SCHEMBL27389069 | 0.72 | TSHR (0.46) | — | |
| SCHEMBL1176245 | 0.72 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | claimed |
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | claimed |
| WO-2020242960-A1 | COMPOUNDS TARGETING PROTEINS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2020-12-03 | — | — | WO | claimed |
| WO-2023070120-A1 | KETOAMIDES FOR TREATING MALIGNANCY | BIOTHERYX, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-11345712-B2 | Protein-targeting compounds and pharmaceutical compositions thereof, and their therapeutic applications | BIOTHERYX, INC. (US) | 2022-05-31 | — | — | US | disclosed |
| CN-114502543-A | Targeted protein compounds, pharmaceutical compositions and therapeutic applications thereof | 拜欧斯瑞克斯公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-109096320-B | Method for preparing benzoyl coriolide | 黄冈鲁班药业股份有限公司 | 2021-04-16 | — | — | CN | disclosed |
| WO-2020242960-A1 | COMPOUNDS TARGETING PROTEINS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. (US) | 2020-12-03 | — | — | WO | disclosed |
| US-20200369679-A1 | PROTEIN-TARGETING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2020-11-26 | — | — | US | disclosed |
| EP-1892256-B1 | AROMATIC POLYMER | SUMITOMO CHEMICAL CO (JP) | 2014-03-19 | — | — | EP | disclosed |
| CN-101218277-B | Aromatic polymer | SUMITOMO CHEMICAL CO | 2012-03-07 | — | — | CN | disclosed |
| US-20020048645-A1 | Dipyrromethene-metal chelate compound and optical recording medium using thereof | MITSUI CHEMICALS, INCORPORATED (JP) | 2002-04-25 | — | — | US | disclosed |
| EP-1130584-A2 | Dipyrromethene-metal chelate compound and optical recording medium using thereof | Mitsui Chemicals, Inc. (JP) | 2001-09-05 | — | — | EP | disclosed |
| EP-0906324-B1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AG (DE) | 2001-08-01 | — | — | EP | disclosed |
| US-6242583-B1 | COUPLING CARBOHYDRATE COMPOUNDS IN PRESENCE OF PROMOTER TO A FUNCTIONALIZED SOLID SUPPORT | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-05 | — | — | US | disclosed |
| EP-0906324-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-07 | — | — | EP | disclosed |
| EP-0888262-A1 | CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997045436-A1 | CARBOHYDRATE DERIVATIVES AND THEIR SOLID-PHASE SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 1997-12-04 | — | — | WO | disclosed |
| WO-1997034852-A1 | CYCLOALKYL DERIVATIVES AND THE SOLID-PHASE SYNTHESIS OF SUCH DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-25 | — | — | WO | disclosed |
| US-4307034-A | ALKYLATION | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 1981-12-22 | — | — | US | disclosed |