Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6048332 | 0.92 | MAPK1 (0.35) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL1538376 | 0.87 | RIPK1 (0.42) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL9491108 | 0.82 | RIPK1 (0.34) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL11707316 | 0.81 | RIPK1 (0.35) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL6281493 | 0.80 | TSHR (0.43) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL18884474 | 0.77 | PTPN5 (0.42) | RIPK1CHRM2ADRA1ASLC6A4ADRA2A | |
| SCHEMBL6277396 | 0.76 | KEAP1 (0.40) | LMNAALDH1A1MAPK1 | |
| SCHEMBL4981503 | 0.75 | LMNA (0.35) | RIPK1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL348336 | 0.73 | — | — | |
| SCHEMBL8939782 | 0.72 | TYR (0.39) | TAAR1ADRA2AADRA2CCYP2D6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175423-A4 | WEAKLY COORDINATING ANIONS CONTAINING POLYFLUOROALKOXIDE LIGANDS | UNIV COLORADO STATE RES FOUND (US) | 2002-10-25 | — | — | EP | disclosed |
| EP-1175423-A1 | WEAKLY COORDINATING ANIONS CONTAINING POLYFLUOROALKOXIDE LIGANDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000053611-A1 | WEAKLY COORDINATING ANIONS CONTAINING POLYFLUOROALKOXIDE LIGANDS | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2000-09-14 | — | — | WO | disclosed |