SCHEMBL3483642

SCHEMBL3483642

Cc1c(O)cc2c(=O)c3ccccc3sc2c1C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
MAPT P10636 6/20 0.64
POLB P06746 3/20 0.64
L3MBTL1 Q9Y468 3/20 0.64
LMNA P02545 2/20 0.64
HCRTR1 O43613 2/20 0.64
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
GAA P10253 1/20 0.55
MAOA P21397 3/20 0.48
MAOB P27338 1/20 0.48
KDM4E B2RXH2 4/20 0.44
RAB9A P51151 3/20 0.44
NPC1 O15118 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
ALOX15 P16050 1/20 0.44
ESR2 Q92731 2/20 0.43
ESR1 P03372 1/20 0.43
MAPK1 P28482 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30161811 1.00 ALDH1A1 (0.64) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL10001873 0.84 ALDH1A1 (0.60) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL8086595 0.84 ALDH1A1 (0.63) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL11994220 0.81 ALDH1A1 (0.64) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL24949823 0.79 ALDH1A1 (0.54) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL30161909 0.79 MAPT (0.61) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL3484127 0.79 MAPT (0.53) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL1041154 0.78 MAPT (1.00) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL28655643 0.78 ALDH1A1 (0.72) ALDH1A1MAPTPOLBL3MBTL1LMNA
SCHEMBL30162025 0.76 ALDH1A1 (0.64) ALDH1A1MAPTPOLBL3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230032881-A1 ACTIVE ENERGY RAY POLYMERIZATION INITIATOR, ACTIVE ENERGY RAY CURING COMPOSITION, ACTIVE ENERGY RAY CURING INK, AQUEOUS ACTIVE ENERGY RAY CURING INK, CONTAINER, IMAGE FORMING DEVICE, IMAGE FORMING METHOD, AND METHOD OF MANUFACTURING ACTIVE ENERGY RAY POLYMERIZATION INITIATOR RICOH COMPANY, LTD. (JP) 2023-02-02 US disclosed
US-11174239-B2 PEGylated thioxanthone photoinitiator and photosensitive resin composition JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2021-11-16 US disclosed
CN-108424498-B Acrylamide copolymer and preparation method and application thereof 中国石油化工股份有限公司 2021-04-13 CN disclosed
CN-108424490-B Acrylamide copolymer and preparation method and application thereof 中国石油化工股份有限公司 2020-12-18 CN disclosed
CN-108424497-B Acrylamide copolymer and preparation method and application thereof 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-108424499-B Acrylamide copolymer and preparation method and application thereof 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-108424493-B Acrylamide copolymer and preparation method and application thereof 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-108084299-B Composition with polymerization initiating function and method for preparing acrylamide copolymer 中国石油化工股份有限公司 2020-11-10 CN disclosed
CN-108084298-B Composition with polymerization initiating function and method for preparing acrylamide copolymer 中国石油化工股份有限公司 2020-07-24 CN disclosed
US-20200131147-A1 PEGYLATED THIOXANTHONE PHOTOINITIATOR AND PHOTOSENSITIVE RESIN COMPOSITION JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2020-04-30 US disclosed
EP-0844255-A1 PHOTOPOLYMERIZATION INITIATOR AND ACTINIC RADIATION-CURABLE COMPOSITION COMPRISING THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1998-05-27 EP disclosed
EP-0224967-B1 THIOXANTHONE DERIVATIVES WARD BLENKINSOP AND COMPANY LIMITED (GB) 1989-07-19 EP disclosed
US-4791213-A PHOTOINITIATORS WARD BLENKINSOP & COMPANY LIMITED (GB) 1988-12-13 US disclosed
EP-0224967-A1 Thioxanthone derivatives WARD BLENKINSOP AND COMPANY LIMITED (GB) 1987-06-10 EP disclosed
EP-0079119-B1 WATER SOLUBLE THIOXANTHONE PHOTOINITIATORS Sericol Group Limited (GB) 1985-12-27 EP disclosed
EP-0081280-B1 PHOTOPOLYMERISABLE MATERIALS FOR USE IN PRODUCING STENCILS FOR SCREEN PRINTING Sericol Group Limited (GB) 1985-12-11 EP disclosed
US-4459416-A Water soluble thioxantone photoinitiators SERICOL GROUP LIMITED (GB) 1984-07-10 US disclosed
US-4418138-A THIOXANTHONE PHOTOINITIATORS SERICOL GROUP LIMITED (GB) 1983-11-29 US disclosed
EP-0081280-A1 Photopolymerisable materials for use in producing stencils for screen printing Sericol Group Limited (GB) 1983-06-15 EP disclosed
EP-0079119-A1 Water soluble thioxanthone photoinitiators Sericol Group Limited (GB) 1983-05-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11174239-B2 PEGylated thioxanthone photoinitiator and photosensitive resin composition PTGES3, HTR3D, PTMA ALDH1A1 1133/4885MAPT 1309/4885POLB 2799/4885
US-20200131147-A1 PEGYLATED THIOXANTHONE PHOTOINITIATOR AND PHOTOSENSITIVE RESIN COMPOSITION PTGES3, HTR3D, PTMA ALDH1A1 1133/4885MAPT 1309/4885POLB 2799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.