Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 3/20 | 0.53 |
| ▸ | PAM | P19021 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Acetate SCHEMBL3310609 | 1.00 | DGKA (0.56) | DGKAPRKCAPAMLMNAKDM4E | |
| Heptane SCHEMBL15968770 | 0.96 | ALDH1A1 (0.52) | DGKAPRKCAPAMLMNAKDM4E | |
| Heptane SCHEMBL2346183 | 0.96 | ALDH1A1 (0.52) | DGKAPRKCAPAMLMNAKDM4E | |
| Hexane SCHEMBL2346139 | 0.95 | ALDH1A1 (0.54) | DGKAPRKCAPAMLMNAKDM4E | |
| Hexane SCHEMBL5329217 | 0.95 | ALDH1A1 (0.54) | DGKAPRKCAPAMLMNAKDM4E | |
| Ethyl Acetate SCHEMBL4168022 | 0.93 | DGKA (0.56) | DGKAPRKCAPAMLMNAKDM4E | |
| Ethyl Acetate SCHEMBL1614072 | 0.93 | DGKA (0.64) | DGKAPRKCAPAMLMNAKDM4E | |
| Ethyl Acetate SCHEMBL756143 | 0.93 | DGKA (0.64) | DGKAPRKCAPAMLMNAKDM4E | |
| Ethyl Acetate SCHEMBL1777438 | 0.93 | DGKA (0.64) | DGKAPRKCAPAMLMNAKDM4E | |
| Hexane SCHEMBL19611429 | 0.93 | DGKA (0.64) | DGKAPRKCAPAMLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471789-A1 | FUSED HETEROCYCLIC RING DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2012-07-04 | — | — | EP | disclosed |
| US-20100004238-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100004238-A1 | FUSED HETEROCYCLIC COMPOUND | ERBB2, ROS1, FLT3 | DGKA 2444/4885PRKCA 775/4885PAM 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.