Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485153 | 1.00 | CTSB (0.44) | CTSBTSHRTDP1L3MBTL1MMP3 | |
| SCHEMBL2071265 | 1.00 | CTSB (0.44) | CTSBTSHRTDP1L3MBTL1MMP3 | |
| SCHEMBL27604046 | 0.90 | TSHR (0.47) | CTSBTSHRMEN1KMT2ATAAR1 | |
| SCHEMBL28145970 | 0.82 | TDP1 (0.43) | TSHRTDP1L3MBTL1MMP3MMP1 | |
| SCHEMBL18616451 | 0.81 | TSHR (0.52) | CTSBTSHRTDP1L3MBTL1MMP3 | |
| SCHEMBL18940894 | 0.81 | TSHR (0.44) | CTSBTSHRTDP1L3MBTL1MMP3 | |
| SCHEMBL20692515 | 0.80 | TDP1 (0.40) | CTSBTSHRTDP1L3MBTL1MMP3 | |
| SCHEMBL7627184 | 0.80 | TSHR (0.50) | CTSBTSHRMEN1KMT2ATAAR1 | |
| SCHEMBL121000 | 0.80 | TSHR (0.50) | CTSBTSHRMEN1KMT2ATAAR1 | |
| SCHEMBL5228321 | 0.80 | TSHR (0.50) | CTSBTSHRMEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003732-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 2-SUBSTITUTED PROPANAL DERIVATIVE | KANEKA CORPORATION (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-1887085-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 2-SUBSTITUTED PROPANAL DERIVATIVE | Kaneka Corporation (JP) | 2008-02-13 | — | — | EP | disclosed |