Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.53 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GGT1 | P19440 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639955 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL10341609 | 0.84 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL38660686 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL1966422 | 0.83 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL27762366 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL27784009 | 0.81 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL11127664 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL1130035 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL1982429 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDESR1 | |
| SCHEMBL6266872 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240216229-A1 | SELF-ADHESIVE FISSURE SEALANT | KULZER GMBH (DE) | 2024-07-04 | — | — | US | claimed |
| EP-4312947-A1 | SELF-ADHESIVE FISSURE SEALANT | Kulzer GmbH (DE) | 2024-02-07 | — | — | EP | claimed |
| US-20230026650-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | DENTSPLY SIRONA INC. (US) | 2023-01-26 | — | — | US | claimed |
| EP-3834805-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | DENTSPLY SIRONA Inc. (US) | 2021-06-16 | — | — | EP | claimed |
| EP-1765876-A4 | INVERSE EMULSION POLYMER AND METHOD OF USE THEREOF | NALCO CO (US) | 2008-12-03 | — | — | EP | claimed |
| EP-1765876-A1 | INVERSE EMULSION POLYMER AND METHOD OF USE THEREOF | Nalco Company (US) | 2007-03-28 | — | — | EP | claimed |
| US-7115674-B2 | Dental self-curing resin cement compositions | DENTKIST, INC. (KR) | 2006-10-03 | — | — | US | claimed |
| WO-2006004745-A1 | INVERSE EMULSION POLYMER AND METHOD OF USE THEREOF | NALCO COMPANY (US) | 2006-01-12 | — | — | WO | claimed |
| US-20060004130-A1 | Inverse emulsion polymer and method of use thereof | ECOLAB USA INC. | 2006-01-05 | — | — | US | claimed |
| US-20050049326-A1 | Dental self-curing resin cement compositions | DENTKIST, INC. (KR) | 2005-03-03 | — | — | US | claimed |
| US-20040176496-A1 | Light-curing dental adhesive compositions | DENTKIST, INC. (KR) | 2004-09-09 | — | — | US | claimed |
| US-6583197-B1 | Excellent sustained release of fluorine; free radical polymerizable unsaturated monomer having an acid group, acid-reactive fluoroaluminsilicate glass filler, water, solvent | KABUSHIKI KAISHA SHOFU (JP) | 2003-06-24 | — | — | US | claimed |
| US-5834532-A | BLEND OF POLYMERIZABLE MONOMER HAVING ACIDIC GROUPS AND AN INITIATOR | SUN MEDICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | claimed |
| US-5587406-A | APPLYING CURABLE PRIMER COMPOSITION COMPRISING POLYMERIZABLE MONOMER HAVING ACID GROUP AND POLYMERIZABLE MONOMER HAVING HYDROXYL GROUP AND POLYMERIZATION INITIATOR TO TOOTH | SUN MEDICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | claimed |
| EP-0241295-B1 | PHARMACEUTICAL COMPOSITION FOR USE IN DESENSITIZING HYPERSENSITIVE DENTIN | Masuhara, Eiichi (JP) | 1992-08-12 | — | — | EP | claimed |
| US-4911922-A | Pharmaceutical composition for use in desensitizing hypersensitive dentin | EIICHI MASUHARA (JP) | 1990-03-27 | — | — | US | claimed |
| US-4781913-A | Pharmaceutical composition for use in desensitizing hypersensitive dentin | Masuhara, Eiichi (JP) | 1988-11-01 | — | — | US | claimed |
| EP-0241295-A2 | Pharmaceutical composition for use in desensitizing hypersensitive dentin | Masuhara, Eiichi (JP) | 1987-10-14 | — | — | EP | claimed |
| JP-2009807-A | — | — | None | — | — | JP | disclosed |
| EP-0241295-A2 | Pharmaceutical composition for use in desensitizing hypersensitive dentin | Masuhara, Eiichi (JP) | 1987-10-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176496-A1 | Light-curing dental adhesive compositions | HBG2, GRIN2A, HBG1 | KDM4E 3638/4885ALDH1A1 23/4885HSD17B10 2508/4885 |
| US-20240216229-A1 | SELF-ADHESIVE FISSURE SEALANT | ESD, GFER, FUS | KDM4E 2920/4885ALDH1A1 318/4885HSD17B10 1806/4885 |
| US-20230026650-A1 | DENTAL RESIN MODIFIED GLASS-IONOMER COMPOSITION AND KIT COMPRISING SAID COMPOSITION | KIT, PIP5K1C, GRIK1 | KDM4E 481/4885ALDH1A1 1628/4885HSD17B10 4353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.