Phosphoric Acid

Phosphoric Acid

SCHEMBL3486089

O=P(O)(O)O.On1nc2ccccc2n1

nearest known ligand 0.44

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
HPGD P15428 1/20 0.44
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
DDAH1 O94760 1/20 0.36
LMNA P02545 1/20 0.36
FDPS P14324 2/20 0.36
GGPS1 O95749 1/20 0.36
POLB P06746 1/20 0.35
MAPK1 P28482 1/20 0.35
ATM Q13315 1/20 0.35
HTT P42858 1/20 0.35
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SRC P12931 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL103176 0.87 KDM4E (0.55) KDM4EHPGDNPC1RAB9ALMNA
Ammonia Solution, Strong SCHEMBL2472975 0.85 KDM4E (0.52) KDM4EHPGDNPC1RAB9ALMNA
Water SCHEMBL994995 0.85 KDM4E (0.52) KDM4EHPGDNPC1RAB9ALMNA
Phosphoric Acid SCHEMBL3486195 0.78 KMT2A (0.33) KDM4ENPC1RAB9ALMNAFDPS
SCHEMBL28636611 0.78 KDM4E (0.46) KDM4EHPGDNPC1RAB9ALMNA
Benzophenone SCHEMBL8429418 0.76 ALDH1A1 (0.58) KDM4EHPGDNPC1RAB9ALMNA
Phosphoric Acid SCHEMBL3486158 0.76 KDM4E (0.41) KDM4ENPC1RAB9ALMNAGGPS1
SCHEMBL3486091 0.71 SRC (0.39) KDM4EHPGDCA2CA4CA5A
SCHEMBL4633983 0.71 HPGD (0.48) KDM4EHPGDNPC1RAB9ALMNA
Quinoxaline SCHEMBL10841319 0.70 ALDH1A1 (0.44) HPGDCA2CA4CA5ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100029008-A1 POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES FEBIT BIOTECH GMBH (DE) 2010-02-04 US claimed
EP-1828217-A2 POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES Febit Biotech GmbH (DE) 2007-09-05 EP claimed
WO-2006063717-A2 POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES FEBIT BIOTECH GMBH (DE) 2006-06-22 WO claimed
US-20100029008-A1 POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES FEBIT BIOTECH GMBH (DE) 2010-02-04 US disclosed
EP-1828217-A2 POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES Febit Biotech GmbH (DE) 2007-09-05 EP disclosed
WO-2006063717-A2 POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES FEBIT BIOTECH GMBH (DE) 2006-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100029008-A1 POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES POLB, POLM, POLN KDM4E 4045/4885HPGD 2044/4885CA2 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.