SCHEMBL348615

SCHEMBL348615

CCCCC(C=O)CCCC

nearest known ligand 0.80

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.80
SMN1; SMN2 Q16637 1/20 0.80
DNM1 Q05193 2/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
FDPS P14324 1/20 0.39
ADH1B P00325 2/20 0.38
ADH1C P00326 2/20 0.38
ADH1A P07327 2/20 0.38
ADH7 P40394 2/20 0.38
ADH4 P08319 1/20 0.38
CTSK P43235 4/20 0.37
CA2 P00918 2/20 0.37
MAPK1 P28482 1/20 0.37
TRPA1 O75762 1/20 0.37
DDAH1 O94760 1/20 0.37
GAPDH P04406 1/20 0.37
MAPT P10636 1/20 0.37
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8391264 0.95 TSHR (0.73) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL1410522 0.95 TSHR (0.73) TSHRSMN1; SMN2DNM1ALDH1A1CYP3A4
SCHEMBL29291467 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL729815 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL10491642 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL29291473 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL28418848 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL2926136 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL9257929 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL9714408 0.92 TSHR (0.70) TSHRSMN1; SMN2DNM1FDPSADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102985425-A Novel homopiperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use thereof LEO PHARMA AS 2013-03-20 CN claimed
CN-111358713-B copolymer 宝丽化学工业有限公司 2023-09-19 CN disclosed
CN-111481469-B copolymer 宝丽化学工业有限公司 2023-09-19 CN disclosed
WO-2023067125-A1 OLIGOSACCHARIDE COMPLEXES AND USES BioNTech SE (DE) 2023-04-27 WO disclosed
WO-2023067121-A1 OLIGOSACCHARIDE COMPOUNDS AND COMPLEXES BioNTech SE (DE) 2023-04-27 WO disclosed
WO-2023067123-A1 OLIGOSACCHARIDE COMPLEXES AND USES BioNTech SE (DE) 2023-04-27 WO disclosed
CN-111329788-B Copolymer 宝丽化学工业有限公司 2023-03-31 CN disclosed
CN-111329787-B Copolymer 宝丽化学工业有限公司 2023-03-31 CN disclosed
CN-110007561-B Green photosensitive resin composition, color filter and image display device 东友精细化工有限公司 2022-07-19 CN disclosed
CN-109790284-B Polyphenol compound and process for producing the same 三菱化学株式会社 2021-09-21 CN disclosed
WO-2002030858-A1 IMPROVEMENT OF A COLOUR INDEX OF MULTIVALENT ALCOHOLS BY HYDROGENATION BASF AKTIENGESELLSCHAFT (DE) 2002-04-18 WO disclosed
EP-0905217-A1 Unleaded gasoline for direct injection gasoline engine NIPPON OIL CO. LTD. (JP) 1999-03-31 EP disclosed
WO-1997041088-A1 PROCESS FOR PREPARING MONOESTERS OF 1,3-DIOLS NESTE OYJ (FI) 1997-11-06 WO disclosed
US-5072057-A Isomeric alcohol mixture for producing plasticizers and surfac tants EXXON RESEARCH & ENGINEERING CO. (US) 1991-12-10 US disclosed
US-5030774-A Reacting petroleum distillates with carbon monoxide and hydrogen to form aldehyde in presence of carbonyl compounds hydrogenation to form alcohols EXXON RESEARCH AND ENGINEERING CO. (US) 1991-07-09 US disclosed
US-4922028-A Process for the hydroformylation of sulfur-containing thermally cracked petroleum residue and novel products thereof EXXON RESEARCH & ENGINEERING COMPANY (US) 1990-05-01 US disclosed
EP-0329670-A1 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF. EXXON RESEARCH ENGINEERING CO (US) 1989-08-30 EP disclosed
EP-0329670-A4 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF. EXXON RESEARCH ENGINEERING CO (US) 1989-08-16 EP disclosed
US-4853486-A Method for production of dithiodialdehyde NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1989-08-01 US disclosed
WO-1988002360-A1 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF EXXON RESEARCH AND ENGINEERING COMPANY (US) 1988-04-07 WO disclosed