SCHEMBL1410522

SCHEMBL1410522

CCCCC(C=O)CCC

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
CTSK P43235 4/20 0.39
DNM1 Q05193 2/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
FDPS P14324 1/20 0.36
ADH1B P00325 2/20 0.35
ADH1C P00326 2/20 0.35
ADH1A P07327 2/20 0.35
ADH7 P40394 2/20 0.35
ADH4 P08319 1/20 0.35
CA2 P00918 2/20 0.34
MAPK1 P28482 1/20 0.34
TRPA1 O75762 1/20 0.34
DDAH1 O94760 1/20 0.34
GAPDH P04406 1/20 0.34
MAPT P10636 1/20 0.34
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348615 0.95 TSHR (0.80) TSHRSMN1; SMN2CTSKDNM1ALDH1A1
SCHEMBL547296 0.92 TSHR (0.62) TSHRSMN1; SMN2FDPSADH1BADH1C
SCHEMBL29291465 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL28625479 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL28625631 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL9320445 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL6925908 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL29291468 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL277792 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B
SCHEMBL2925442 0.90 TSHR (0.60) TSHRSMN1; SMN2DNM1FDPSADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4448171-B1 TRANSITION METAL COMPLEX HYDROFORMYLATION CATALYST PRECUROR COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND HYDROFORMYLATION PROCESSES DOW TECHNOLOGY INVESTMENTS LLC (US) 2025-08-20 EP disclosed
EP-4448170-B1 COMPOUNDS, TRANSITION METAL COMPLEX HYDROFORMYLATION CATALYST PRECUROR COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND HYDROFORMYLATION PROCESSES DOW TECHNOLOGY INVESTMENTS LLC (US) 2025-08-20 EP disclosed
US-20250128245-A1 COMPOUNDS, TRANSITION METAL COMPLEX HYDROFORMYLATION CATALYST PRECUROR COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND HYDROFORMYLATION PROCESSES DOW TECHNOLOGY INVESTMENTS LLC (US) 2025-04-24 US disclosed
US-12246310-B2 Processes for recovery of rhodium from a hydroformylation process DOW TECHNOLOGY INVESTMENTS LLC (US) 2025-03-11 US disclosed
US-20250019334-A1 HYDROFORMYLATION PROCESS FOR PREPARING LINEAR AND BRANCHED ALDEHYDES NORTH CAROLINA STATE UNIVERSITY 2025-01-16 US disclosed
EP-4054762-B1 PROCESSES FOR RECOVERY OF RHODIUM FROM A HYDROFORMYLATION PROCESS DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-12-18 EP disclosed
US-20240399349-A1 TRANSITION METAL COMPLEX HYDROFORMYLATION CATALYST PRECUROR COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND HYDROFORMYLATION PROCESSES DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-12-05 US disclosed
EP-3710161-B1 PROCESSES FOR RECOVERY OF RHODIUM FROM A HYDROFORMYLATION PROCESS DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-10-16 EP disclosed
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES DOW TECHNOLOGY INVESTMENTS LLC (US) 2024-05-30 US disclosed
WO-2024107323-A1 HETEROGENEOUS CATALYSTS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-23 WO disclosed
EP-0366561-A2 1-Azabicycloalkane derivatives, process for their preparation and their use as medicines ROUSSEL-UCLAF (FR) 1990-05-02 EP disclosed
US-4922028-A Process for the hydroformylation of sulfur-containing thermally cracked petroleum residue and novel products thereof EXXON RESEARCH & ENGINEERING COMPANY (US) 1990-05-01 US disclosed
EP-0329670-A1 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF. EXXON RESEARCH ENGINEERING CO (US) 1989-08-30 EP disclosed
US-4861918-A RHODIUM-TERITARY ORGANOPHOSPHINE COMPLEX UNION CARBIDE CORPORATION (US) 1989-08-29 US disclosed
EP-0329670-A4 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF. EXXON RESEARCH ENGINEERING CO (US) 1989-08-16 EP disclosed
US-4757147-A Imino-substituted piperidine compound PETROLITE CORPORATION (US) 1988-07-12 US disclosed
WO-1988002360-A1 A PROCESS FOR THE HYDROFORMYLATION OF SULFUR-CONTAINING THERMALLY CRACKED PETROLEUM RESIDUA AND NOVEL PRODUCTS THEREOF EXXON RESEARCH AND ENGINEERING COMPANY (US) 1988-04-07 WO disclosed
US-4625068-A STERICALLY HINDERED PHOSPHINE LIGNANDS; CATALYSTS EXXON CHEMICAL PATENTS INC. (US) 1986-11-25 US disclosed
EP-0195656-A1 Improved rhodium catalyzed hydroformylation of internal olefins EXXON CHEMICAL PATENTS INC. (US) 1986-09-24 EP disclosed
US-4020109-A POLYMERIZATION AND ALDOL CONDENSATION INHIBITION UNION OIL COMPANY OF CALIFORNIA (US) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250019334-A1 HYDROFORMYLATION PROCESS FOR PREPARING LINEAR AND BRANCHED ALDEHYDES CYP2F1, HOGA1, HAO2 TSHR 3547/4885SMN1; SMN2 2394/4885CTSK 3653/4885
US-20250128245-A1 COMPOUNDS, TRANSITION METAL COMPLEX HYDROFORMYLATION CATALYST PRECUROR COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND HYDROFORMYLATION PROCESSES C1R, M6PR, FOLR1 TSHR 359/4885SMN1; SMN2 2120/4885CTSK 2746/4885
US-20240399349-A1 TRANSITION METAL COMPLEX HYDROFORMYLATION CATALYST PRECUROR COMPOSITIONS COMPRISING SUCH COMPOUNDS, AND HYDROFORMYLATION PROCESSES M6PR, KRAS, C1R TSHR 3827/4885SMN1; SMN2 1997/4885CTSK 1908/4885
US-20240174583-A1 PROCESSES FOR THE VAPOR PHASE HYDROGENATION OF ALDEHYDES ADH1C, ADH5, ALDH2 TSHR 4679/4885SMN1; SMN2 1192/4885CTSK 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.