Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.61 |
| ▸ | NPY1R | P25929 | 3/20 | 0.58 |
| ▸ | NPY2R | P49146 | 3/20 | 0.58 |
| ▸ | NPY4R | P50391 | 3/20 | 0.58 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.57 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.55 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466124 | 1.00 | GHSR (0.61) | GHSRNPY1RNPY2RNPY4RKISS1R | |
| SCHEMBL29434320 | 1.00 | GHSR (0.61) | GHSRNPY1RNPY2RNPY4RKISS1R | |
| SCHEMBL3486226 | 1.00 | GHSR (0.61) | GHSRNPY1RNPY2RNPY4RKISS1R | |
| SCHEMBL29388140 | 0.94 | GHSR (0.55) | GHSRNPY1RNPY2RNPY4RKISS1R | |
| SCHEMBL29534023 | 0.94 | GHSR (0.55) | GHSRNPY1RNPY2RNPY4RKISS1R | |
| SCHEMBL14509563 | 0.91 | GHSR (0.65) | GHSRNPY1RNPY2RNPY4RKISS1R | |
| SCHEMBL31404052 | 0.90 | GHSR (0.68) | GHSRNPY1RNPY2RNPY4RKISS1R | |
| SCHEMBL21185972 | 0.90 | IL23R (0.65) | KISS1RIL23R | |
| SCHEMBL16358972 | 0.88 | GHSR (0.61) | GHSRUTS2R | |
| SCHEMBL30053610 | 0.88 | GHSR (0.71) | GHSRNPY1RNPY2RNPY4RUTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035822-A1 | PROLINE-RICH PEPTIDES, PHARMACEUTICAL COMPOSITION, USE OF ONE OR MORE PEPTIDES AND METHOD OF TREATMENT | PEP FARMA CONSULTORIA E DESENVOLVIMENTO FARMACEUTI (BR) | 2010-02-11 | — | — | US | disclosed |
| EP-1979373-A2 | PROLINE-RICH PEPTIDES, PHARMACEUTICAL COMPOSITION, USE OF ONE OR MORE PEPTIDES AND METHOD OF TREATMENT | PEP Farma Consultoria e Desenvolvimento Farmacêutico Ltda (BR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007079558-A2 | PROLINE-RICH PEPTIDES, PHARMACEUTICAL COMPOSITION, USE OF ONE OR MORE PEPTIDES AND METHOD OF TREATMENT | PEP FARMA CONSULTORIA E DESENVOLVIMENTO FARMACÊUTICO LTDA (BR) | 2007-07-19 | — | — | WO | disclosed |